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CHEM 433: Medicinal Chemistry and Drug Development
3.00 Credits
Case Western Reserve University
This course provides an overview on how principles in chemistry and biology are integrated to facilitate drug development. Primary emphasis will be placed on the development of organic molecules as drugs and metabolic enzymes as drug targets. Subjects pertinent to the introduction of medicinal chemistry, evaluation of drug efficacies in vitro and in vivo, and drug metabolism will be covered. Offered as CHEM 333 and CHEM 433.
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CHEM 433 - Medicinal Chemistry and Drug Development
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CHEM 435: Synthetic Methods in Organic Chemistry
3.00 Credits
Case Western Reserve University
Systematic consideration of reactions involving functional group transformations and carbon-carbon bond formations used in modern organic synthesis. Recommended preparation: Two semesters of undergraduate organic chemistry.
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CHEM 435 - Synthetic Methods in Organic Chemistry
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CHEM 436: Complex Molecular Synthesis
3.00 Credits
Case Western Reserve University
An advanced organic chemistry course providing students with an in-depth examination of the art of total synthesis drawing from both classical and recent examples. Recommended preparation: Two semesters of undergraduate organic chemistry.
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CHEM 436 - Complex Molecular Synthesis
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CHEM 439: Bioinorganic Chemistry
3.00 Credits
Case Western Reserve University
An introduction to metal ions in biology and medicine. Topics of emphasis include metalloenzymes, inorganic elements in pharmaceuticals, and physical methods of characterization in biology. Course material will be presented through a seminar format, and will involve extensive class participation, student presentations, and literature research reports. Offered as CHEM 339 and CHEM 439. Prereq: Graduate standing.
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CHEM 439 - Bioinorganic Chemistry
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CHEM 445: Electrochemistry I
3.00 Credits
Case Western Reserve University
Electrochemical properties and processes of electrode/electrolyte interfaces. Fundamental background for work in corrosion, electrodeposition, industrial electrolysis, electro-organic synthesis, batteries, fuel cells, and photoelectrochemical energy conversion. Recommended preparation: One semester of undergraduate physical chemistry.
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CHEM 445 - Electrochemistry I
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CHEM 446: Quantum Mechanics I
3.00 Credits
Case Western Reserve University
Introduction of quantization, measurement and the Schrodinger equation; angular momentum and states of molecules. Perturbation theory, spectroscopy and chemical bonding. Variational theory and calculations of molecular properties. Recommended preparation: Two semesters of undergraduate physical chemistry. Offered as CHEM 335 and CHEM 446.
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CHEM 446 - Quantum Mechanics I
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CHEM 447: Quantum Mechanics II
3.00 Credits
Case Western Reserve University
Continuation of CHEM 446. Ab initio and semi-empirical methods, configuration interactions, time dependent phenomena, and introduction to band theory of solids. Prereq: CHEM 446.
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CHEM 447 - Quantum Mechanics II
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CHEM 450: Molecular Spectroscopy
3.00 Credits
Case Western Reserve University
Translation, rotation, vibration, and electronic transitions of molecules. Prereq: CHEM 446.
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CHEM 450 - Molecular Spectroscopy
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CHEM 475: Protein Biophysics
3.00 Credits
Case Western Reserve University
This course focuses on in-depth understanding of the molecular biophysics of proteins. Structural, thermodynamic and kinetic aspects of protein function and structure-function relationships will be considered at the advanced conceptual level. The application of these theoretical frameworks will be illustrated with examples from the literature and integration of biophysical knowledge with description at the cellular and systems level. The format consists of lectures, problem sets, and student presentations. A special emphasis will be placed on discussion of original publications. Offered as BIOC 475, CHEM 475, PHOL 475, PHRM 475, and NEUR 475.
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CHEM 475 - Protein Biophysics
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CHEM 491: Modern Chemistry for Innovation I
3.00 Credits
Case Western Reserve University
The first half of a two-semester sequence providing an understanding of chemistry as a basis for successfully launching new high-tech ventures. The course will examine physical limitations to present technologies and the use of chemistry to identify potential opportunities for new venture creation. The course will provide experience in using chemistry for both identification of incremental improvements and as the basis for alternative technologies. Case studies will be used to illustrate recent commercially successful (and unsuccessful) venture creation and will illustrate characteristics for success. Admission to this course requires consent of the department.
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CHEM 491 - Modern Chemistry for Innovation I
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