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Course Criteria
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3.00 Credits
A one-semester lecture covering classical and modern aspects of the analytical process; analysis requirements, method selection including capabilities and limitations, sampling and sample processing, measurement data statistics for evaluation of precision and accuracy, method validation, and reporting. Fundamental concepts in equilibrium thermodynamics are covered in the context of chemical analysis. Methods based on titration, spectroscopy, electrochemistry, chromatography, and mass spectrometry are emphasized. Prereq: CHEM 106 and CHEM 113. Coreq: CHEM 304.
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3.00 Credits
Fundamentals of inorganic chemistry. Topics include molecular structure, molecular shape and symmetry, structure of solids, d-metal complexes, oxidation and reduction, and acids and bases. Prereq or Coreq: CHEM 301 or CHEM 335.
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3.00 Credits
Continuation of CHEM 311. Fundamentals of inorganic chemistry. Topics include electronic spectra of complexes, structures and properties of solids, organometallic compounds, and descriptive chemistry of representative elements. Prereq: CHEM 311.
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3.00 Credits
Experimental approach to the synthesis, purification and characterization of organic compounds. Nuclear magnetic resonance (NMR) and infrared (IR) spectroscopies; chromatographic techniques. Prereq: CHEM 304 and CHEM 223 or CHEM 323. Prereq or Coreq: CHEM 224 or CHEM 324.
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3.00 Credits
Relationships between molecular structure and chemical reactivity and development of sophisticated problem-solving skills in the context of organic reaction mechanisms and multi-step synthesis. Homolytic and heterolytic substitution, elimination, oxidation and reduction reactions; topics in stereochemistry and spectroscopy. Recommended for chemistry, biochemistry, and related majors. Prereq: CHEM 106 or equivalent.
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3.00 Credits
Continuation of CHEM 323. Introduces the chemistry of carbonyl, aromatic and amino functional groups, and develops the concepts of conjugation and resonance, molecular orbital theory and pericyclic reactions. Prereq: CHEM 223 or CHEM 323.
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3.00 Credits
Structure determination of organic compounds using mass spectrometry and modern instrumental techniques such as infrared, ultraviolet, visible, and nuclear magnetic resonance spectroscopy. Recommended preparation: Two semesters of undergraduate organic chemistry. Offered as CHEM 325 and CHEM 425.
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3.00 Credits
A survey of biochemistry with a strong emphasis on the chemical logic underlying metabolic pathways and the evolution of biomolecules. Cellular architecture. Amino acids and protein structure, purification, analysis, and synthesis. DNA, RNA, the flow of genetic information, and molecular biological technology. Enzyme kinetics, catalytic, and regulatory strategies. Sugars, complex carbohydrates, and glycoproteins. Lipids and cell membranes. Glycolysis, gluconeogenesis, carbon fixation through the "dark reactions" of photosynthesis, aerobic catabolism through the citric acid cycle, and glycogen metabolism. Biosynthesis and degradation of fatty acids, amino acids, and proteins. Offered as CHEM 328 and CHEM 428. Prereq: CHEM 224 or CHEM 324.
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3.00 Credits
A survey of biochemical systems exploring their molecular circuitry and architecture. Protein structure and function. Lipids, cell membranes, channels and pumps. Redox processes and electron transport. Lipid and carbohydrate metabolism, its control, reciprocal regulation, and global integration. Nucleotide biosynthesis, DNA replication, recombination, and repair. RNA synthesis, splicing, and translation: protein synthesis and the control of gene expression. Sensory and immune systems. Molecular motors. Recommended preparation: Two semesters of undergraduate organic chemistry and one semester of undergraduate physical chemistry. Offered as CHEM 329 and CHEM 429.
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3.00 Credits
Synthesis, separation techniques, physical properties, and analysis. Advanced techniques of chemical synthesis, leading the student to the preparation of interesting inorganic and organometallic compounds. Prereq: CHEM 322.
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