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Course Criteria
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3.00 Credits
Climate changes and natural selection, prior to human activities, have pre-equipped autotrophic organisms with a suite of adaptations to natural abiotic stress. Whether these adaptations are capable of dealing with current and future levels (magnitude, speed) of non-natural abiotic change is of great interest. This course will examine, in detail, the tight physiological interactions between plants and their variable environment. Emphasizing major aspects of indirect (UV-B, global warming, altered precipitation) and direct (CO2, O3, SOx, NOx) anthropogenic pollution, relevant plant cellular processes, and responses of plants to abiotic stress, will be examined. With this foundation, class discussions will explore scaled collective consequences of global change to plant-dominated terrestrial and aquatic ecosystems. Offered as BIOL 353 and BIOL 453.
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3.00 Credits
This graduate level course will examine biological interactions that result inorganismal coadaptation and its ecological implications. Darwin was an avid observer of biological interactions that result inorganismal coadaptation and its ecological implications. Darwin was an avid observer of biological interactions and his theory of evolution by natural selection focused primarily on one type of interaction; competition between individuals especially those of the same species. However, Darwin did not explicitly consider the role of cooperation in biological evolution. Nonetheless, cooperation can be a key agent in the coadaptation of organisms and in fact may have led to the evolution of eukaryotes. Three broad types of interactions will be examined in this course: competition, parasitism and cooperation. A particular focus of the course will be on biological cooperation or mutualism. Case studies will be presented to highlight the possible range of biological coadaptation. Lectures will be supplemented by discussion of the relevant literature.
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3.00 Credits
The goal of this course is to provide a basic working knowledge of protein structure/function and molecular biology. The course begins with a discussion of protein structure and enzyme catalysis followed by protein purification and characterization. The course then addresses concepts relating to the application of modern molecular biology techniques. Students are taught how to clone genes and use these clones in animal and cell-based studies. The overall goal is to provide students with an understanding of proteins and genetic approaches that can be used in experimental work and to facilitate comprehension of the scientific literature. Offered as BIOL 457 and PHOL 456.
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4.00 Credits
Ultimately the success or failure (i.e., life or death) of any individual animal is determined by its behavior. The ability to locate and capture food, avoid being food, acquiring and defending territory, and successfully passing your genes to the next generation, are all dependent on complex interactions between an animal's design, environment and behavior. This course will be an integrative approach emphasizing experimental studies of animal behavior. You will be introduced to state-of-the-art approaches to the study of animal behavior, including neural and hormonal mechanisms, genetic and developmental mechanisms and ecological and evolutionary approaches. We will learn to critique examples of current scientific papers, and learn how to conduct observations and experiments with real animals. We will feature guest appearances by the Curator of Research from the Cleveland MetroParks Zoo and visits to working animal behavior research labs here at CWRU. Group discussions and writing will be emphasized. This course satisfies a laboratory requirement for biology majors. Offered as BIOL 358 and BIOL 458.
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3.00 Credits
In this course, students will discuss scientific papers on Drosophila behavior. Emphasis will be given to studies that employ the powerful genetic tools available in Drosophila to the study of behavior. The topics covered will include: innate behaviors (e.g. sexual behavior); learning and memory; sensory information processing; anatomy of the Drosophila adult brain; genetic screenings for behavioral mutants; genetic tools to interfere with behavioral response. Students will be required to write and develop an objective project that combines genetics with behavioral tests. Students will be graded in presentations as well as a final grant proposal. Lab component will consist of experimentation in files using genetics and behavioral analyses, to be carried out in the last 6 weeks of the course. Counts as a Biology laboratory course for the B.A. and B.S. Biology degrees. Offered as BIOL 359 and BIOL 459. Prereq: BIOL 216 or BIOL 251.
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3.00 Credits
Same as BIOL 362 except the required term paper is an NIH-format research proposal. Recommended preparation: BIOL 216. Offered as ANAT 462 and BIOL 462.
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3.00 Credits
This laboratory course will teach concepts and techniques in developmental biology. Emphasis will be on the mechanisms that pattern the embryo during development and how these mechanisms are explored using molecular, cellular, and genetic approaches. A term research paper is required. Students taking the graduate level course will prepare a grant proposal. One laboratory and one lecture per week. Offered as BIOL 363 and BIOL 463.
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3.00 Credits
The process of evolution explains not only how the present diversity of life on earth has formed, but also provides insights into current pressing issues today, including the spread of antibiotic resistance, the causes of geographic variation in genetic diseases, and explanations for modern patterns of extinction risk. Students in Research Methods in Evolutionary Biology will be introduced to several of the major research approaches of evolutionary biology, including methods of measuring natural selection on the phenotypic and genotypic levels, quantifying the rate of evolution, reconstructing evolutionary relationships, and assessing the factors that affect rates of speciation and extinction. The course will consist of a combination of interactive lectures, in-class problem solving and data analysis, and the discussion of peer-reviewed scientific papers. Grades are based on participation in class, discussions and written summaries of published papers, in-class presentations, and two writing assignments. Offered as BIOL 364 and BIOL 464. Prereq: BIOL 214, BIOL 216, BIOL 251.
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3.00 Credits
This discussion-based course offers a detailed introduction to Evolutionary Developmental Biology. The field seeks to explain evolutionary events through the mechanisms of Developmental Biology and Genetics. The course is structured into different modules. First we will look at the developmental genetic mechanisms that can cause variation. Then we focus on how alterations of these mechanisms can generate novel structural changes. We will then examine a few areas of active debate, where Evo-Devo is attempting to solve major problems in evolutionary biology. We will conclude with two writing assignments. Students will be required to present, read, and discuss primary literature in each module. Offered as BIOL 365 and BIOL 465.
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3.00 Credits
Many exciting research opportunities cross disciplinary lines. To participate in such projects, researchers must operate in multi-disciplinary teams. The Biorobotics Team Research course offers a unique capstone opportunity for undergraduate students to utilize skills they developed during their undergraduate experience while acquiring new teaming skills. A group of eight students form a research team under the direction of two faculty leaders. Team members are chosen from appropriate majors through interviews with the faculty. They will research a biological mechanism or principle and develop a robotic device that captures the actions of that mechanism. Although each student will cooperate on the team, they each have a specific role, and must develop a final paper that describes the research generated on their aspect of the project. Students meet for one class period per week and two 2-hour lab periods. Initially students brainstorm ideas and identify the project to be pursued. They then acquire biological data and generate robotic designs. Both are further developed during team meetings and reports. Final oral reports and a demonstration of the robotic device occur in week 15. Offered as BIOL 377, EMAE 377, BIOL 477, and EMAE 477.
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