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  • BIOL 225: Evolution

    3.00 Credits
    Case Western Reserve University

    Multidisciplinary study of the course and processes of organic evolution provides a broad understanding of the evolution of structural and functional diversity, the relationships among organisms and their environments, and the phylogenetic relationships among major groups of organisms. Topics include the genetic basis of micro- and macro-evolutionary change, the concept of adaptation, natural selection, population dynamics, theories of species formation, principles of phylogenetic inference, biogeography, evolutionary rates, evolutionary convergence, homology, Darwinian medicine, and conceptual and philosophic issues in evolutionary theory. Offered as ANTH 225, BIOL 225, EEPS 225, HSTY 225, and PHIL 225.
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  • BIOL 240: Personalized Medicine

    3.00 Credits
    Case Western Reserve University

    The emphasis of clinical practice is slowly shifting from one-disease and one-treatment-fits-all to more personalized care based on molecular markers of disease risk, disease subtype, drug effectiveness, and adverse drug reactions. This course, designed for non-biology majors, will introduce how the developments in gene sequencing, genetic markers, and stem cells can be applied for predictive testing and personalized therapies. Core concepts to be covered include the principles of genetics including the inheritance of traits determined by single genes and by multiple genes, the assignment of risk to particular genetic constitutions, and the nature and use of stem cells. The emergence of private companies as resources for the performance of the tests, and how the general public will be able to interpret their own data (with or without the access to genetic counselors), will also be covered. The course will include hands-on laboratory experiences of DNA manipulation and detection using the polymerase chain reaction and gel electrophoresis. The ethical, legal, and social issues associated with personal genetic testing will also be covered. This course does not count towards any Biology degree, nor towards the Biology minor.
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  • BIOL 250: Introduction to Cell and Molecular Biology Systems

    3.00 Credits
    Case Western Reserve University

    This course will emphasize an understanding of living organisms at the cellular level from a molecular view point. Topics to be covered will include: unity and diversity of living things, evolutionary relatedness, cells, tissues and organelles, life as a biochemical process, molecular building blocks of life, gene structure and function, uses of model organisms and molecular experimental methods. The topics to be covered are relevant to current practices in biotechnology, medicine and agriculture and these connections will be highlighted. This course is not open to students who have received credit for BIOL 214 and/or BIOL 215.
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  • BIOL 251: Introduction to Organismal and Population Systems

    3.00 Credits
    Case Western Reserve University

    This course will emphasize an understanding of the regulation of the structure and function of organismal and population systems. Adopting an evolutionary perspective, the course will provide students with a comparative analysis of plant and animal solutions to the problem of multicellularity. Detailed exploration of animals will focus on the development of tissue and organ systems and their coordination at an organismal level. This systems approach will then be extended to regulation of ecosystems and abundance of organisms in populations.
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  • BIOL 300: Dynamics of Biological Systems: A Quantitative Introduction to Biology

    3.00 Credits
    Case Western Reserve University

    This course will introduce students to dynamic biological phenomena, from the molecular to the population level, and models of these dynamical phenomena. It will describe a biological system, discuss how to model its dynamics, and experimentally evaluate the resulting models. Topics will include molecular dynamics of biological molecules, kinetics of cell metabolism and the cell cycle, biophysics of excitability, scaling laws for biological systems, biomechanics, and population dynamics. Mathematical tools for the analysis of dynamic biological processes will also be presented. Students will manipulate and analyze simulations of biological processes, and learn to formulate and analyze their own models. This course satisfies a laboratory requirement for the biology major. Offered as BIOL 300 and EBME 300.
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  • BIOL 301: Biotechnology Laboratory: Genes and Genetic Engineering

    3.00 Credits
    Case Western Reserve University

    Laboratory training in recombinant DNA techniques. Basic microbiology, growth, and manipulation of bacteriophage, bacteria and yeast. Students isolate and characterize DNA, construct recombinant DNA molecules, and reintroduce them into eukaryotic cells (yeast, plant, animal) to assess their viability and function. Two laboratories per week. Offered as BIOL 301 and BIOL 401. Prereq: BIOL 215 or BIOL 250.
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  • BIOL 302: Human Learning and the Brain

    3.00 Credits
    Case Western Reserve University

    This course focuses on the question, "How does the human brain learn?" Through assigned readings, extensive class discussions, and a major paper, each student will explore personal perspectives on learning. Specific topics include, but are not limited to: the brain's cycle of learning; neocortex structure and function; emotion and limbic brain; synapse dynamics and changes in learning; images in cognition; symbolic brain (language, mathematics, music); memory formation; and creative thought and brain mechanisms. The major paper will be added to each student's SAGES writing portfolio. In addition, near the end of the semester, each student will make an oral presentation on a chosen topic. Offered as: BIOL 302 and COGS 322.
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  • BIOL 303: Principles of Chemical Biology

    4.00 Credits
    Case Western Reserve University

    This is a computer-assisted course and offers a detailed introduction into biological macromolecular structure and function with particular emphasis on proteins. Computer-assisted learning will follow each lecture and will involve either searching the Web for appropriate sources of information covered in the lecture or using spreadsheets and graphics to examine data extracted from the chemical biology and biomedical literature. For example, the protein database (PDB) and Rasmol software will be used to visualize and measure biological macromolecules and extracted data from the biomedical literature will be analyzed by standard graphical procedures employing the computer. This new format will offer the student the ability to learn to use the information resources on the Web together with the computing ability of the computer to explore the concepts presented in the course. This course satisfies a laboratory requirement for the biology major. Prereq: CHEM 105 and CHEM 106 or CHEM 111 and ENGR 145.
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  • BIOL 304: Fitting Models to Data: Maximum Likelihood Methods and Model Selection

    3.00 Credits
    Case Western Reserve University

    This course will introduce students to maximum likelihood methods for fitting models to data and to ways of deciding which model is best supported by the data (model selection). Along the way, students will learn some basic tenets of probability and develop competency in R, a commonly used statistical package. Examples will be drawn from ecology, epidemiology, and potentially other areas of biology. The second half of the course is devoted to in-class projects, and students are encouraged to bring their own data. Offered as BIOL 304 and BIOL 404. Prereq: MATH 121 and MATH 122 OR MATH 125 and MATH 126.
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  • BIOL 305: Herpetology

    4.00 Credits
    Case Western Reserve University

    Amphibians and reptiles exhibit tremendous diversity in development, physiology, anatomy, behavior and ecology. As a result, amphibians and reptiles have served as model organisms for research in many different fields of biology. This course will cover many aspects of amphibian and reptile biology, including anatomy, evolution, geographical distribution, physiological adaptations to their environment, reproductive strategies, moisture-, temperature-, and food-relations, sensory mechanisms, predator-prey relationships, communication (vocal, chemical, behavioral), population biology, and the effects of venomous snake bite. Laboratory sessions will be devoted to learning species identification and evolutionary relationships, discussion of the ecology of Ohio's amphibians and reptiles, survey techniques for determining population size and structure, and observations of the behavior of live reptiles and amphibians. Laboratory sessions may include trips to Squire Valleevue Farm, Cleveland Museum of Natural History, and Cleveland Metroparks Zoo. Prereq: BIOL 214 or BIOL 251.
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