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Course Criteria
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3.00 Credits
Students study human body kinematics, force analysis of joints, and the structure and composition of biological materials. Emphasis is placed on the measurement of mechanical properties and the development and understanding of models of biological material mechanical behavior.
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3.00 Credits
Engineering principles as applied to the cardiovascular system. Anatomy of cardiovascular system; form and function of blood and blood vessels. Electric analogs; continuum mechanics with derivation of equations of motion; and constitutive models of soft tissue mechanics, with attention to normal, diseased, and adaptive processes. Programming project required. Credit is not allowed for both BME 443 and BME 543.
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3.00 Credits
Design concepts of engineering problems: objectives, specifications, manufacturing, prior art, and analysis. Oral and written exercises in reverse engineering. Lectures in national and international standards, quality control, intellectual propertylaw, and engineering ethics. Team projects to design, build, and deliver a prototype device to aid a disabled person or other appropriate biomedical engineering project that provides an opportunity for real world engineering design and community outreach.
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3.00 Credits
Continuation of BME 451. Project analysis, design, scheduling, construction, and testing. Advanced written and oral technical communication. Teamwork and the function of engineering design in society. Major team project with a biomedical engineering theme.
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3.00 Credits
In-depth study of the engineering design of biomedical polymers and implants. Polymeric biomaterials, including polymer synthesis and structure, polymer properties as related to designing orthopedic and vascular grafts. Designing textile products as biomaterials including surface modification and characterization techniques. Bioresorbable polymers.
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3.00 Credits
Application of engineering and biological principles to understand the structure and performance of tendons, ligaments, skin, and bone; bone mechanics; viscoelasticity of soft biological tissues; models of soft biological tissues; mechanics of skeletal muscle; and tissue-derived devices as well as interfaces between native tissues and synthetic devices.
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3.00 Credits
Overview of microcontroller-based systems, including applications, architecture, number systems, and languages. Students gain experience using a PIC-based microcontroller to input information from a user and output information using LEDs and LCD displays. Student will learn capabilities of the PIC through in class exercises and weekly programming assignments. Both assembly language and PIC-based C are used. Students develop a PIC-based heart rate monitor and work in pairs on a BME-related project of their choice.
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2.00 Credits
In this half-semester laboratory module, students will gain practical experience with two key elements of tissue engineering: tissue building and angiogenesis. Using advanced culture techniques, students will construct a complex living tissue that closely resembles its natural counterpart, then assess its ability to support ingrowth of capillaries (angiogenesis). The effects of different biomaterials and angiogenic factors will be evaluated. The engineered tissue will be embedded, sectioned and stained for histological analysis.
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3.00 Credits
This course covers essential concepts of organ and tissue design and engineering using living components, including cell-based systems and cells/tissues in combination with biomaterials, synthetic materials and/or devices. Topics include: In vivo tissue structure and function; Isolation and culture of primary cells and stem cells; Principles of cellular differentiation; Mass transport processes in cell culture systems; Design, production and seeding of scaffolds for 3D culture; Design of bioreactors to support high-density cell growth; State-of-the-art engineered tissue systems; Clinical translation; and Ethics.
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1.00 - 4.00 Credits
Offered as needed for presenting material not normally available in regular BME Department courses or for new BME courses on a trial basis.
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