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Course Criteria
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1.00 Credits
For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research.
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1.00 - 3.00 Credits
For students who have completed all credit hours, full-time enrollment, preliminary examination, and residency requirements for the doctoral degree, and are writing and defending their dissertations.
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3.00 Credits
Curricular bridge between high school and college for high school and transitional students. Fundamental cell biology concepts pertaining to biomanufacturing. Students gain an understanding of the basic principles of microbiology, culture preparation, physiology, and genetics of microbial cell cultures. Team-based decisions, collaborations and consideration of multiple perspectives are emphasized. Practical experience in laboratory and culture techniques used in biomanufacturing. Transportation will be provided for field trips. This course is part of the Summer College in Biotechnology and Life Sciences (SCIBLS), as well as other pre-college, transitional and early-college programs. Suitable for students with less than 30 credit hours.
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1.00 Credits
Introduction to discovery and development of biopharmaceuticals, industrial enzymes, food ingredients and biologics. Discussion of majors that prepare students for positions in the biotechnology industry. Lectures from staff and from professionalsin the biotechnology industry focus on drug development, biopharmaceutical process development, design of biomanufacturing facilities, overview of methods used for manufacturing biopharmaceuticals, drug and enzyme purification, formulation, as well as careers in FDA compliance documentation related to manufacturing products using microbial biotechnology.
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2.00 Credits
This is a half-semester course. This introductory module addresses fundamental cell biology concepts and enables students to gain an understanding of the basic principles of microbiology, culture preparation, physiology and genetics of microbial cell cultures. The lab portion of the course provides students with practical experience in basic laboratory and culture techniques. Students who have completed either MB 352 or MB 354 may not take this course for credit.
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2.00 Credits
Objectives, strategies, and approaches for recovery and purification of biomolecules, especially recombinant proteins. Description of common purification equipment, processes and materials used for cell lysis, precipitation, flocculation, membrane filtration, column chromatography, and centrifugation. Laboratories provide students with exposure to various techniques and the parameters that control protein isolation and purification of a recombinant protein. This is a half-semester course. Students who have completed BIT(CHE) 464 may not complete this course for credit.
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2.00 Credits
This is a half-semester course. Basic microbial cell culture theory and practice: cell physiology, mass balances, and metabolic control as seen in a dynamic bioreactor process to be scalable, consistent, and robust. The lab portion of the course provides students with hands-on experience in culture techniques using bioreactors. Students who have completed MB(BEC) 520 may not take BEC (MB) 420 for credit.
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2.00 Credits
Objectives, strategies, and approaches for recovery and purification of biomolecules, especially recombinant proteins. Laboratories in the intermediate-scale pilot plant provide students with exposure to various unit operations and the parameters that control protein isolation and purification of a recombinant protein produced by an E. coli. This is a half-semester course. Students who have completed BEC 436 may not take BEC 536 for credit.
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3.00 Credits
Introduction to various expression systems, their advantages and disadvantages. Basic techniques in DNA cloning, cell transformation and optimization of protein expression. Selection, archiving and characterization of production line. Media development and parameters affecting expression and yield. The lab portion of the course provides students with practical experience in DNA cloning and protein expression techniques in diverse expression systems.
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2.00 Credits
Introduction to the insect cells expression system, and its advantages and disadvantages. Introduction to expression of recombinant proteins with baculovirus. Outline of antibody and antibody fragments as well as other complex proteins. Basic techniques used for growth and maintenance of insect cell cultures. The lab portion of the course provides students with practical experience in protein expression techniques in the insect cells expression system. This is a half-semester course. Students who have completed BEC 442 may not take BEC 542 for credit.
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