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Course Criteria
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3.00 Credits
Process validation is a tested and documented subset of the panel of activities that are performed during the production of a biopharmaceutical. This course will introduce the concept of process validation as it applies to the biotechnology industry, and more specifically, to the manufacture of protein molecules as therapeutic agents.
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3.00 Credits
Introduction to the structure and functions of microbial cells and their cultivation and utilization in bioprocess engineering. Fermentation systems and downstream processing methods. Enzyme kinetics, production and application. Biomanufacturing of fuels, industrial chemicals, pharmaceuticals, food additives and food products such as beer, wine, cheese and yogurt Microbial biomass production. Introduction to environmental biotechnology including waste water treatment, bioremediation and biomining. Biodeterioration and its control. Product development, regulations and safety. Field trip(s) are an essential educational component of the course and are required. Credit will not be given for both BAE(BBS) 425 and BAE 525.
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2.00 Credits
This course is an introduction to current food manufacturing practice (CGMP) as applied to the growth of microbial cells in bioreactors. Hands-on experience is obtained in the operation and control of 30 liter bioreactors to study agitation, oxygen transfer, cleaning, sterilization, media preparation and the growth of recombinant E. coli for protein production. Credit will not be awarded in both BBS 426 and BBS/FS 526. This is an eight week course.
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2.00 Credits
This course is an introduction to current food manufacturing practice (CGMP) as applied to the growth of microbial cells in bioreactors. Hands-on experience is obtained in the operation and control of 30 liter bioreactors to study agitation, oxygen transfer, cleaning, sterilization, media preparation and the growth of recombinant E. coli for protein production. Credit will not be awarded in both BBS 426 and BBS/FS 526. This is an eight week course.
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3.00 Credits
Curricular bridge between high school and college for high school and transitional students. A "hands on" introduction to fundamentals in Microbiology and Biochemistry. Bacterial isolation, identification and growth using aseptic technique, microscopy, and metabolic analysis. Experiments with DNA isolation and analysis, protein isolation, and purification, and enzyme kinetics. Lectures and readings on background, theory and applications of these techniques. Field trips to university and industry research laboratories. This course is part of the Summer College in Biotechnology and Life Sciences (SCIBLS) as well as other pre-college, transitional and early-college programs and is offered as 4 week intensive course. Applicants should have completed high school courses in biology and chemistry. Students must have completed no more than 30 credit hours. Departmental approval is required for current NCSU students.
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3.00 Credits
Biotechnology and Societing is an introductory science course that takes a semi-technical look at the emerging role of biotechnology in human society. Expectations are that students will gain an appreciation for biotechnology, the ability to understand how biotechnology works. Offered only in Poland through Study Abroad (4-week course). Departmental approval required.
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4.00 Credits
This course is an introduction to the basic principles of biochemistry. It emphasizes biochemical structures, properties, and functions, including enzyme kinetics and major metabolic processes. It discusses amino acids and proteins, carbohydrates, lipids, and nucleic acids. The pathways discussed will include glycolysis, gluconeogenesis, and the Krebs cycle. It can serve as a prerequisite for BCH 452 with permission of the department. This course is designed for those students who are not majoring in Biochemistry and do not require a more comprehensive introduction to biochemistry. It is not intended for graduate students. Credit is not allowed for both BCH 351 and BCH 451.
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4.00 Credits
Introduction to the fundamental principles of biochemistry. Emphasis on biochemical structures, properties, functions and interactions, including enzyme kinetics and central pathways of metabolism.
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2.00 Credits
Laboratory experience to complement BCH 451. Basic skills in the use of volumetric equipment, spectrophotometers, chromatography, and electrophoresis. Manipulation and assay of small quantities of biological materials, and analysis of laboratory data.
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3.00 Credits
Structure and function of nucleic acids and proteins. Synthesis of DNA, RNA, and proteins. Gene expression and Regulation. Methodologies of recombinant DNA research. Credit is not allowed for both BCH 453 and BCH 553.
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