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Course Criteria
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4.00 Credits
In-depth study of cell biology, with an emphasis on the molecular aspects of cell function. Topics include protein structure and synthesis, gene expression and its regulation, cell replication, and specialized cell structure and function. The course provides an introduction to genomics and bioinformatics and examines developmental biology, evolution, and systems biology.
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4.00 Credits
Study of the evolutionary development of backboned animals, with emphasis on the mammals. Treats the major organ systems of vertebrate groups, with stress on structural-functional interpretations. Laboratory work includes detailed dissection of representative vertebrates. Field trips to the American Museum of Natural History help illustrate some of the topics.
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4.00 Credits
A comparative course that encompasses vertebrate and invertebrate physiology. Extensive discussion of the anatomy and physiology of the human cardiovascular system, the human lung, the human kidney, and the human brain. There is a focus on the physiological integration of organ systems, underlying cellular/molecular mechanisms, and adaptation. Ventilation, organism scale and environment, blood, the cardiovascular system, acid-base regulation, osmoregulation, feeding, digestion and absorption, the nervous system and behavior, muscle, endocrine function, and reproduction are studied. Special topics include human physiology in extreme environments (high-altitude and diving), a detailed analysis of mammalian vision, animal sleep and hibernation, and the comparative physiology of animals that live at deep-sea hydrothermal vents. The laboratory includes traditional physiology experiments, as well as an introduction to bioinformatics.
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4.00 Credits
Introduction to the principles and experimental strategies of developmental biology. Covers the cellular and molecular basis for pattern in the embryo; the determination of cell fate; cell differentiation; the genes controlling these events; how they are identified and studied; and the cellular proteins that affect shape, movement, and signaling between cells. Special emphasis on the experimental basis for our knowledge of these subjects from studies in fruit flies, nematodes, frogs, plants, and mice.
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4.00 Credits
This advanced-level course covers three themes in experimental physiology: molecular and cellular systems; nervous and endocrine control of systems; and organ and body systems. The basic structure and function for each system is examined in an experimental setting to show how a particular system contributes to maintaining homeostasis. Through student-designed experiments, the course introduces the technical foundations of experimental design, critical data analysis, and modeling. Professional skills are honed via readings in the current literature, preparing and presenting research talks, and writing formal papers.
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4.00 Credits
An introductory course in genetics covering classical genetics, chromosome structure and mutation, gene function and regulation, and aspects of molecular and developmental genetics. Recent studies in human genetics and their applications are also discussed.
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4.00 Credits
Covers genetic principles by means of a projectbased laboratory. Students characterize mutants genetically and phenotypically. Analyses of dominance, linkage, recombination, dosage effects, and complementation are performed in the first part of the course. The second part of the course addresses genetic approaches made possible by the availability of complete genome sequences (genomics). Special note: Although the class is held at the listed hours (as described on Albert) and attendance at the start of each class session is mandatory, the biological nature of the work may require some laboratory time outside the scheduled laboratory session.
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4.00 Credits
Genetics is now widely used to understand the nervous system. This course begins with an introduction to neuronal function and communication and then turns to a study of how neurons function in sensory perception (e.g., olfaction) and behavior (e.g., circadian rhythms). In these, the course highlights the role of genetics in identifying key genes and in manipulating specific neurons to understand their function by introducing classic papers from the primary literature. Students also learn how to design novel experiments that build on these papers. The course concludes with examples of human nervous system pathologies with genetic bases. Current Topics in Earth System Science: Mass
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4.00 Credits
Intermediate course in the molecular basis of gene action in viruses, prokaryotes, and eukaryotes. Covers topics drawn from the following areas or other current work: structure and organization of the genetic material, replication, repair, transcription, translation, recombination, oncogenesis, and regulation of gene expression.
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4.00 Credits
Designed to provide background and practical experience in scanning electron, transmission electron, fluorescent, and phase/DIC microscopy. The principles and theory of the various types of microscopes currently available are discussed. A histological overview of various tissues is studied in regard to their cellular structure and function. Optical and computational methods of image processing useful to the biomedical scientist are also explored. At the Bench: Applied Molecular Biology
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