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  • 15 122J: Critical Reading and Technical Assessment of Biomedical Information

    1.00 Credits
    Massachusetts Institute of Technology

    Gain experience in critical reading of scientific literature, including patents, journal articles and FDA labels, with an emphasis on analyzing clinical controversies and emerging technologies in subject areas that have been or could become sources of entrepreneurial activity. Students required to analyze a variety of topics in the scientific literature, including screening for and cost-effectiveness of early detection of cancer, therapeutic opportunities in oncology, evaluation of immunotoxins and antibody therapies, and new prospects for the treatment of autoimmune disorders. To support the discussion of these topics, outside experts may be invited to participate as facilitators. Prerequisite:    Prereq: SB degree in Biological Science or permission of instructor
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  • 15 123J: Dynamics of Biomedical Technologies

    2.00 Credits
    Massachusetts Institute of Technology

    Covers topics in biomedical enterprise. Provides instruction on how to identify research problems in the area; to develop testable hypotheses regarding such problems and design strategies for testing them; and, when applicable, to report progress in implementing these strategies. Includes presentations by individuals drawn from the biomedical industry, by faculty who study the industry, and by students. Enrollment may be limited. Prerequisite:    Prereq: None
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  • 15 124J: Evaluating a Biomedical Business Concept

    1.00 Credits
    Massachusetts Institute of Technology

    Teams of students evaluate a clinical need and develop an effective process for turning this need into a business. Topics include alternative solutions, intellectual property protection, market opportunity, regulatory and reimbursement hurdles, competitive threats, and potential return on investment. Students are encouraged to interview clinicians, potential customers and other stakeholders, as well as consultants and competitors. Teams present a series of analyses and solutions to each of the critical issues faced. Enrollment limited. Prerequisite:    Prereq: HST.971
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  • 15 127J: Designing and Sustaining Technology Innovation for Global Health Practice

    0.00 - 6.00 Credits
    Massachusetts Institute of Technology

    Course trains students to think and act like global health leaders and entrepreneurs. Looks at the business of running a social venture and how to plan and provide access to life-saving medicines and essential services in international and domestic settings. Considers specific case studies for influential and leading edge technologies for health services delivery, as well as human resources, and pharmaceutical and diagnostic design in resource-poor settings. Features lectures and skills-based tutorial sessions led by industry, foundation, and academic leaders. Lectures provide the foundation for a design project that may involve creation of a market or business plan, product design specification, or research study. Limited to 24. Prerequisite:    Prereq: None
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  • 15 128J: Neurotechnology Ventures

    2.00 Credits
    Massachusetts Institute of Technology

    Special seminar focusing on the challenges of envisioning, planning, and building start-ups that are commercializing innovations from neuroscience and the blossoming domain of neuroengineering. Topics include neuroimaging and diagnostics, psychophysiology, rehab feedback, affective computing, neurotherapeutics, surgical tools, neuropharmaceuticals, deep brain stimulation, prosthetics and neurobionics, artificial senses, nerve regeneration, and more. Each class is devoted to a specific topic area. The first hour covers the topic in survey form. The second hour is dedicated to a live case study of a specific organization. A broad spectrum of issues, from the deeply technical through market opportunity, is explored in each class. Prerequisite:    Prereq: Permission of instructor
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  • 15 136J: Principles and Practice of Drug Development

    3.00 Credits
    Massachusetts Institute of Technology

    Description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules. Economic and financial considerations of the drug development process. Multidisciplinary perspective from faculty in clinical; life; and management sciences; as well as industry guests. Prerequisite:    Prereq: Permission of instructor
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  • 15 137J: Case Studies and Strategies in Drug Discovery and Development

    2.00 Credits
    Massachusetts Institute of Technology

    The stages in drug discovery and development begin with target identification and end with the submission of preclinical and clinical data to the regulatory authorities. Following identification of a lead compound, there is optimization of structures for pharmaceutical properties, bioavailability, and safety. Subject relies on actual cases presented by the scientist(s) involved in discovery and drug development. A major goal is to analyze the cases and determine how the discovery and development process might be influenced by new and future technologies. Prerequisite:    Prereq: Permission of instructor
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  • 15 141J: Economics of the Health Care Industries

    3.00 Credits
    Massachusetts Institute of Technology

    Focuses on economic issues in various health care and allied industries, such as the pharmaceutical, biotechnology, medical device, vaccine and diagnostic sectors. Addresses differences between health care and other industries; regulatory issues, in the US and globally, that involve establishment of the efficacy and cost-effectiveness of treatments; managing those who manage research and development; policies to incentivize research and development for neglected tropical diseases; strategic issues in global pricing and marketing; use of e-commerce and information technology; and formation and management of various alliances. Visiting speakers from academia, government, non-government organizations (non-profits), and industry. Assignments include 4 to 6 essays; no final exam. Prerequisite:    Prereq: Permission of instructor
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  • 15 218: Global Economic Challenges and Opportunities

    3.00 Credits
    Massachusetts Institute of Technology

    Begins with analysis of financial crises?from historical examples in emerging markets, to the Great Depression, to the recent global crisis. Topics include bubbles, financial contagion, capital controls, currency mismatch and crisis prediction. Remainder of the subject explores major global economic challenges and evaluates policy responses. Topics include unsustainable debt, currency wars, future of the European Union, aging populations, global warming, trade imbalances, inequality and poverty, oil and commodity markets, foreign aid, international institutions, and the implications of rapid growth in the BRICs (Brazil, Russia, India, and China) and "frontier" economies. Some background in international economics recommended. Prerequisite:    Prereq: None
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  • 15 220: Global Strategy and Organization

    3.00 Credits
    Massachusetts Institute of Technology

    Focuses on the international dimensions of strategy and organization, and provides a framework for formulating strategies in an increasingly complex world economy, and for making those strategies work effectively. Topics include the globalization of industries, the continuing role of country factors in competition, organization of multinational enterprises, building global networks, and the changing managerial tasks under conditions of globalization. Prerequisite:    Prereq: None
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