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10 493: Integrated Chemical Engineering Topics II
2.00 Credits
Massachusetts Institute of Technology
No course description available.
Prerequisite:
Prereq: 10.301 and permission of instructor
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10 493 - Integrated Chemical Engineering Topics II
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10 494: Integrated Chemical Engineering Topics III
2.00 Credits
Massachusetts Institute of Technology
Chemical engineering problems presented and analyzed in an industrial context. Emphasizes the integration of fundamentals with material property estimation, process control, product development, and computer simulation. Integration of societal issues, such as engineering ethics, environmental and safety considerations, and impact of technology on society are addressed in the context of case studies. 10.37 and 10.302 required for certain topic modules. See departmental website for individual ICE-T module descriptions.
Prerequisite:
Prereq: 10.301 and permission of instructor
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10 494 - Integrated Chemical Engineering Topics III
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10 495: Molecular Design and Bioprocess Development of Immunotherapies
3.00 Credits
Massachusetts Institute of Technology
Examines challenges and opportunities for applying chemical engineering principles to address the growing global burden of infectious disease, including drug-resistant strains and neglected pathogens. Topics include a historical overview of vaccines and immunotherapies, the molecular design considerations for new immunotherapies and adjuvants, the economic challenges for process development and manufacturing of immunotherapies, and new technologies for designing and assessing therapies. Case studies to cover topics for specific diseases. Students taking graduate version complete additional assignments.
Prerequisite:
Prereq: 7.06 or permission of instructor
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10 495 - Molecular Design and Bioprocess Development of Immunotherapies
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10 499J: Tissue Engineering for Analysis, Prevention, and Treatment of Human Disease
3.00 Credits
Massachusetts Institute of Technology
Analysis of fundamental processes in tissue engineering with an emphasis on use of comparative animal models and in vitro tissue engineered models to understand human disease and develop therapies for human disease and for regenerating human tissues and organs. using representative examples of metabolic tissue (e.g., liver) and connective tissue (e.g., bone). Design principles and engineering approaches (e.g., use of synthetic materials) for controlling receptor-mediated processes such as cell migration, growth, and differentiation. Mass transfer limitations in design of devices for cell encapsulation and in scaffold-guided regeneration. Guided organization of multicellular structures. Current clinical prospects.
Prerequisite:
Prereq: 5.07 or 7.05; 7.03; 18.03; 20.110 or 5.60
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10 499J - Tissue Engineering for Analysis, Prevention, and Treatment of Human Disease
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10 50: Analysis of Transport Phenomena
4.00 Credits
Massachusetts Institute of Technology
Unified treatment of heat transfer, mass transfer, and fluid mechanics, emphasizing scaling concepts in formulating models and analytical methods for obtaining solutions. Topics include conduction and diffusion, laminar flow regimes, convective heat and mass transfer, and simultaneous heat and mass transfer with chemical reaction or phase change.
Prerequisite:
Prereq: 10.301, 10.302
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10 50 - Analysis of Transport Phenomena
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10 52: Mechanics of Fluids
3.00 Credits
Massachusetts Institute of Technology
Advanced subject in fluid and continuum mechanics. Content includes kinematics, macroscopic balances for linear and angular momentum, the stress tensor, creeping flows and the lubrication approximation, the boundary layer approximation, linear stability theory, and some simple turbulent flows.
Prerequisite:
Prereq: 10.50
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10 52 - Mechanics of Fluids
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10 524: Pharmaceutical Engineering
3.00 Credits
Massachusetts Institute of Technology
Presents engineering principles and unit operations involved in the manufacture of small molecules pharmaceuticals, from the isolation of purified active pharmaceutical ingredients (API) to the final production of drug product. Regulatory issues include quality by design and process analytical technologies of unit operations, such as crystallization, filtration, drying, milling, blending, granulation, tableting and coating. Also covers principles of formulation for solid dosage forms and parenteral drugs. Students taking graduate version complete additional assignments. Limited to 50.
Prerequisite:
Prereq: None
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10 524 - Pharmaceutical Engineering
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10 53: Advances in Biomanufacturing
1.00 Credits
Massachusetts Institute of Technology
Seminar examines how biopharmaceuticals, an increasingly important class of pharmaceuticals, are manufactured. Topics range from fundamental bioprocesses to new technologies to the economics of biomanufacturing. Also covers the impact of globalization on regulation and quality approaches as well as supply chain integrity. Students taking graduate version complete additional assignments.
Prerequisite:
Prereq: None
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10 53 - Advances in Biomanufacturing
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10 531J: Macromolecular Hydrodynamics
3.00 Credits
Massachusetts Institute of Technology
Physical phenomena in polymeric liquids undergoing deformation and flow. Kinematics and material functions for complex fluids; techniques of viscometry, rheometry; and linear viscoelastic measurements for polymeric fluids. Generalized Newtonian fluids. Continuum mechnanics, frame invariance, and convected derivatives for finite strain viscoelasticity. Differential and integral constitutive equations for viscoelastic fluids. Analytical solutions to isothermal and non-isothermal flow problems; the roles of non-Newtonian viscosity, linear viscoelasticity, normal stresses, elastic recoil, stress relaxation in processing flows. Introduction to molecular theories for dynamics of polymeric fluids. (Extensive class project and presentation required instead of a final exam).
Prerequisite:
Prereq: 2.25, 10.301, or permission of instructor
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10 531J - Macromolecular Hydrodynamics
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10 536J: Thermal Hydraulics in Power Technology
3.00 Credits
Massachusetts Institute of Technology
Emphasis on thermo-fluid dynamic phenomena and analysis methods for conventional and nuclear power stations. Kinematics and dynamics of two-phase flows. Steam separation. Boiling, instabilities, and critical conditions. Single-channel transient analysis. Multiple channels connected at plena. Loop analysis including single and two-phase natural circulation. Subchannel analysis.
Prerequisite:
Prereq: 2.006, 10.302, 22.312, or permission of instructor
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10 536J - Thermal Hydraulics in Power Technology
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