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Course Criteria
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3.00 Credits
This course introduces students to original research in cell biology. Students learn how to use the scientific literature and online databases to design and conduct experiments on an original research question involving the stress responses of model organisms. Students will work in research teams on projects that are intended generate publication-quality data. Projects will involve cell culture, the generation of transgenic cell lines, light and fluorescence microscopy, analysis of cellular macromolecules and physiological characterization. This course is recommended for students who are interested in pursuing graduate studies or careers in biomedical research.
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3.00 Credits
This course is an advanced project laboratory for hands-on training in the experimental techniques of molecular biology under faculty supervision. In addition to formal lab training and discussions, students will have access to the lab outside class hours to work on projects intended to produce publication quality data. Methods taught include: macromolecular purification, electrophoresis analysis, recombinant DNA and cloning techniques, DNA sequencing, polymerase chain reaction, and the use of computers and national databases for the analysis of DNA and protein sequences. It is ideal for students who desire a solid introduction to the methods of molecular biology through practical training.
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3.00 Credits
This course introduces students to experimental techniques used in modern biochemistry within the context of original investigations. Students will learn methods involved in the separation and characterization of biological macromolecules, including electrophoresis, protein over-expression, HPLC and mass spectroscopy. Students will work in teams on projects that they have designed in consultation with the instructors, with the goal of generating data that will be used in a research publication. Ideal for students interested in gaining practical experience in biochemical research.
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3.00 Credits
This course is an introduction to original research in neurobiology. You will learn about neuroanatomy and neural cell biology, and basic aspects of mammalian cell culture and bioassay analyses. Using primary literature searches, you will design specific experiments to test hypotheses of your own generation. From these experiments you will be able to generate quantitative data, and using basic statistical analyses, you will be able to identify significant versus non-significant changes in your data. This course is recommended for students who are interested in moving on to graduate school or careers in biomedical/pharmaceutical research.
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3.00 Credits
Students will learn fundamental concepts and methods in ecological research by examining processes that structure communities in wetlands. Through lectures, student-led discussions of ecological literature, and group experiments in the field and laboratory, participants will evaluate and apply methods for understanding the structure and function of communities. Experiments will involve measurements of plants in transects along physical gradients in the field, greenhouse studies, biogeochemical measurements, sediment slurries, microscopy, and isotopic enrichments. Successful students will produce publication-quality data and deliver a research poster presentation at the end of the semester. Course is recommended for students interested in graduate studies in ecology.
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3.00 Credits
The fission yeast Schizosaccharomyces pombe is an important model organism for the study of intracellular processes such as cell cycle control, transcription, DNA replication, chromosome maintenance, and signal transduction. This laboratory will involve original molecular genetic research using S. pombe that involves concepts related to forward genetics and gene manipulation. This course is recommended for students interested in pursuing graduate studies or careers in biomedical research.
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3.00 Credits
In this hands-on laboratory, each student will learn the technical skills necessary to undertake research projects on the health and genetic diversity of animal species in New England and various global ecosystems. Techniques learned to accomplish projects will include extraction of DNA and RNA, polymerase chain reaction for analysis of biodiversity and disease prevalence and quantitative real time PCR for analysis of gene expression.
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1.00 Credits
Students participating in the Biology Honors Program meet weekly for a seminar discussing research results and articles from the primary scientific literature.
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1.00 Credits
Students participating in the Biology Honors Program meet weekly for a seminar discussing research results and articles from the primary scientific literature.
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6.00 Credits
See the College of Arts and Sciences section of this Catalog for a description of the Scholar of the College program. This course can count as a maximum of one upper-division elective if no other elective credit has been claimed for other research courses.
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