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  • BIOL 425: Research in Biology

    0.50 Credits
    Trinity College

    Students will conduct original laboratory research projects under the direction of an individual faculty member. Students electing to pursue independent study of this type should plan on initiating work no later than the fall of the senior year, and should also plan on no less than two semesters of study with a final formal report to be submitted to the department, as well as a poster at the annual Science Symposium. Seniors and those using laboratory research to satisfy the Group IV requirement must simultaneously enroll in the Research Seminar (Biology 403). Submission of the special registration form, available in the Registrar's Office, and the approval of the instructor are required for enrollment. 0.50 units, Independent Study
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  • BIOL 428: Bioinformatics

    3.00 Credits
    Trinity College

    The cell is the fundamental unit of life and its function is largely determined by the complete set of proteins that it contains at any given time. Laboratories worldwide aim to describe protein expression levels under different conditions in many cell types from diverse organisms. Related goals include analysis of protein-protein interactions and functional analysis of all proteins. This course will use commercially-available software packages and other advanced technology to search genomic databases, analyze sequence data, evaluate differential expression of proteins, and study protein structure and function relationships. The course is divided into three parts: Protein Synthesis and Structure (from genome to protein), Experimental Methods (2D gel electrophoresis, mass spectrometry, two hybrid methods, micro-array technology), and Bioinformatics Methods (public and private genome and proteome databases, sequence annotation tools, phylogeny and structure analysis, data mining strategies). The clinical implications for development of new therapies and drug discovery will be discussed throughout the semester. Prerequisite: C- or better in Biology 153; Chemistry 112L (or 121) and one of the following: Biology 221, 226, 227, 317, or Chemistry 401 or 404. 1.00 units min / 1.25 units max, Lecture
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  • BIOL 430: Avian Ecology and Conservation

    3.00 Credits
    Trinity College

    This seminar/discussion course will focus on issues related to the ecology and conservation of birds. We will examine current areas of research at several levels, including genetic, species, population, community, and landscape. Class discussions will focus on readings from the current ornithological literature, and class will be organized around student presentations of this material. A research project is required. Prerequisite: C- or better in Biology 233 or 333. 1.00 units, Seminar
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  • BIOL 435: Life History Strategies

    1.00 Credits
    Trinity College

    This seminar and discussion course examines the evolution and consequences of life history strategies for a variety of organisms and at several levels (gene, individual, population). We will discuss adaptations and constraints of various strategies and attempt to integrate current life history theory into the framework of conservation biology. Topics of discussion include evolution of sex, sex ratios, predator-prey relationships, reproductive effort/costs, reproductive schedules, sex reversal, lifespan and senescence, and complex life cycles. Class will be organized around student discussion and presentation of readings from the current literature. Permission of instructor required. 1.00 units, Seminar
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  • BIOL 440: Drug Discovery

    25.00 Credits
    Trinity College

    This lecture/laboratory course introduces students to principles of pharmacology, and explores diverse approaches used to identify new targets for drug action, screening strategies for biological activity and toxicity, and methodologies for studying drug clearance. Students also learn about modern laboratory analysis of traditional medicines, natural compounds with potent biological activity, genetic polymorphisms in drug response and clearance, and the placebo effect. Prerequisite: C- or better in Biology 227 or Biology 308 or Biology 317 or Permission of the Instructor. 1.25 units, Laboratory
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  • BIOL 446: Bacterial Pathogenesis

    0.00 Credits
    Trinity College

    This seminar will examine the intricate relationship between a bacterial pathogen and a mammalian host. Bacteria have evolved a wide array of virulence factors that allow them to circumvent host defense mechanisms and cause disease. Many of these virulence factors have been identified and studied at the molecular level. Additionally, a study of the host immune system is essential for an understanding of the ability of microorganisms to cause disease. The molecular biology of bacterial virulence as well as the host response to pathogens will be examined through readings and discussions of the primary literature. Prerequisite: C- or better in Biology 221 or Biology 224 and at least one of the following: Biology 227, 244, 308, or 317. 1.00 units, Seminar
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  • BIOL 456: Biology of Communication

    3.00 Credits
    Trinity College

    This integrative course will examine the development, neurobiology, physiology, ecology, and evolution of communication in vertebrate animals, including humans. We will discuss how communication signals (e.g., bird songs, human speech, olfactory communication chemicals) are generated by animals, how these signals travel through the environment and are perceived by other animals, and how, in turn, they modify the behavior of the receiving animal. Human disorders such as deafness will be examined as a means of understanding plasticity in communication systems. Emphasis will be on reading and discussing articles from the primary literature. The laboratory section will include both lab and field experiments in which we record and analyze signals, examine hormonal effects on communication behaviors, and observe behavioral responses to playbacks of communication signals. This course includes a community learning component. Prerequisite: C- or better in Biology 319L or Neuroscience 201. 1.25 units, Lecture
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  • BIOL 463: Ecological Concepts and Methods

    25.00 Credits
    Trinity College

    This advanced course utilizes lectures and student-led seminars to explore a variety of ecological topics, ranging from the level of the individual organism to the biosphere. Readings are drawn predominantly from the primary literature. Laboratories, mostly field-based, introduce methodology and emphasize the design of observational and experimental studies. There will likely be one or two mandatory weekend-long lab sessions at a field station. With special permission, the course may be taken without the prerequisite. Prerequisite: C- or better in Biology 333L or Biology 222L. 1.25 units, Lecture
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  • BIOL 464: Molecular Genetics

    0.00 Credits
    Trinity College

    An examination of the current molecular explanations of the structure, maintenance, control, and expression of genes in both prokaryotic and eukaryotic organisms. Biology 227L is recommended. Prerequisite: C- or better in Biology 224 1.00 units, Lecture
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  • BIOL 466: Teaching Assistantship

    0.50 Credits
    Trinity College

    Students who have been invited to serve as teaching assistants will register for this course. Submission of the special registration form, available in the Registrar's Office, and the approval of the instructor are required for enrollment. See paragraph on teaching assistants in the description of the major. Not creditable to the major. 0.50 units, Independent Study
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