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Course Criteria
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4.00 Credits
Lecture, three hours; discussion, one hour. Cells use nano-machines (molecular motors) to organize themselves and transport cargo. This interdisciplinary course studies these motors and the rails they move along. Examines their biological function and how they function at the single-molecule level as machines. Prerequisite: Biological Sciences D103 or consent of instructor. Concurrent with Biological Sciences D115.
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2.00 Credits
Seminar, two hours. Advanced study of various topics in cell biology. Prerequisite: consent of instructor. May be repeated for credit.
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4.00 Credits
Lecture, three hours. Introduction to the use of the mouse in contemporary biomedical research. The biology and development of the laboratory mouse, methods for manipulation of the mouse genome and embryos, and examples of application of these methods to understanding mammalian development and homeostasis. Prerequisite: graduate standing, advanced undergraduate standing, or consent of instructors Same as Biological Chemistry 215.
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1.00 Credits
Seminar, one hour. Students receive formal training in balancing graduate-level biology research with other time commitments, including teaching. Recommended for graduate students who have an active research program and teaching or course work commitments.
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2.00 Credits
Seminar, one and onehalf hours. Advanced topics of current interest in molecular and developmental genetics. May be repeated for credit.
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4.00 Credits
Lecture, three hours. Advanced course on the use of genetic analysis to identify the genes that control cell behavior and development. Formal discussion, by instructor, of genetics and the relationship between genotype and phenotype, followed by student-led discussion based on assigned readings.
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2.00 Credits
Research interests of faculty participating in the graduate program in Molecular Biology, Genetics, and Biochemistry are presented in weekly meetings. Corequisite: enrollment in the graduate program in Molecular Biology, Genetics, and Biochemistry.
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4.00 Credits
Lecture, three hours. An advanced, integrated view of cell biology. Topics include the cell cycle, the cytoskeleton, the extracellular matrix, signal transduction, the cellular basis of development, and the cell biology of cancer. Prerequisite: consent of instructor. Concurrent with Biological Sciences D154.
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4.00 Credits
Lecture, three hours. Development of animal eggs from fertilization until morphological specialization. Emphasis on two processes: pattern formation and morphogenesis. Patterning is studied genetically, experimentally through regeneration, and theoretically. Morphogenesis is analyzed in terms of cell behavior. Attention to the role of extracellular matrices in both processes. Prerequisite: consent of instructor.
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4.00 Credits
Lecture, three hours. Molecular aspects of the structure and function of neurons and glia including neurotransmission, synaptic modulation, and channels. Neural development at the cellular and molecular level including neurogenesis, pattern formation, trophic factors, axonal growth, and synaptic rearrangement. Prerequisite: consent of instructor.
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