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Course Criteria
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4.00 Credits
Lecture, three hours; discussion, one hour. Antibodies, antigens, antigen-antibody reactions, cells and tissues of lymphoreticular and hematopoietic systems, and individual and collective components of cell-mediated and humoral immune response. Prerequisite: Biological Sciences 98 or consent of instructor.
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4.00 Credits
Lecture, three hours; discussion, one hour. Comparative metabolism of small molecules and cell structure and relationship to microbial classification. Macromolecule synthesis and regulation, sporulation, cell division, growth, and effect of antibiotics. Prerequisite: Biological Sciences 98.
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4.00 Credits
Lecture, three hours; laboratory, two hours. The use of theories and methods based on computer science, mathematics, and physics in molecular biology and biochemistry. Basics in biomolecular modeling. Analysis of sequence and structural data of biomolecules. Analysis of biomolecular functions. Prerequisites: Mathematics 2D or 2J or 7 or Biological Sciences 7. Concurrent with Molecular Biology and Biochemistry 223.
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4.00 Credits
Lecture, three hours; discussion, one hour. Replication of viruses in populations, animals, and the host cell. The effects of viral infection on populations, individuals, and specific molecular effects on the target cell. Role of viral infections in cancer and degenerative diseases. Prerequisite: Biological Sciences 99. Formerly Biological Sciences M124.
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4.00 Credits
Lecture, three hours. The mechanisms of viral pathogenesis and of host resistance to viruses are explored in detail. HIV-1 and Influenza-A are used as examples. In each case, viral replication, cytopathic effects, immune response, and viral evasion are discussed. Prerequisites: Biological Sciences M121 or M124A, or consent of instructor; Biological Sciences M122 recommended. Formerly Biological Sciences M162.
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4.00 Credits
Lecture, three hours. Molecular mechanisms of carcinogenesis. Consideration of transformation by DNA tumor viruses, RNA tumor viruses, and chemical carcinogens. Prerequisite: Biological Sciences 99 or consent of instructor.
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4.00 Credits
Lecture, three hours. Basic biochemical and molecular biology of restriction endonucleases. Vectors for recombinant DNA. Cloning of genes. Sequence analysis of genes. Prerequisite: Biological Sciences 98; Biological Sciences 99 recommended.
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4.00 Credits
Lecture, three hours. Introduction to microbial physiology and the molecular mechanisms of microbial disease pathogenesis. Survey of pathogenic microbes and their medical implications. Prerequisites: Biological Sciences 99; Biological Sciences M122 recommended.
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4.00 Credits
Lecture, three hours. Basic principles of magnetic resonance and x-ray crystallography toward the determination of high-resolution biomolecular structures. Prerequisites: Mathematics 2B and consent of instructor. Concurrent with Molecular Biology and Biochemistry 211.
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4.00 Credits
Lecture, three hours; discussion, one hour. Prerequisites: Biological Sciences 97 and 98. Recommended: concurrent enrollment in Biological Sciences 99.
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