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Course Criteria
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4.00 Credits
How does an endogenous protein become an infectious agent in mad cow disease? How do antibodies trigger immune responses to such a wide range of antigens? How can eating the wrong part of a puffer fish kill you? Answering these questions requires an understanding of how a protein's structure(s) affects its function or dysfunction. Among the topics explored in this seminar are methods of solving, predicting, and visualizing protein structures; structural motifs; conformational change; and proteins' interactions with one another, small molecules, and membranes. Prerequisite: Biology 301 (may be taken concurrently) or permission of the instructor.
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4.00 Credits
Cancer is a genetic disease that cannot be inherited; a disease in which one's own cells disrupt normal physiological functions; a disease for which some therapies result in the loss of the body's ability to fight disease. This advanced course looks at the complex reasons for these paradoxes, and more, by examining a particular cancer from several perspectives: epidemiological, physiological, genetic, molecular, and cellular. A seminar-style approach is taken, in which both text and the primary literature sources are used to examine issues of cancer cause, progression, and treatment. Students are expected to present primary literature articles and to write a research paper on a type of cancer. Prerequisites: Moderation in biology and permission of the instructor.
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4.00 Credits
This course familiarizes the student with the newly emerging science of restoration ecology, including its theoretical foundation and its application in today's world. The course includes a review of the conceptual bases of restoration ecology, including succession, recruitment, plant/ animal interactions, and landscape-scale phenomena. It also addresses particular operational problems in restoration (genetics, hydrological regimes, physical barriers, exotic species, fire, and grazing). The first part of the course concerns case studies and the second part of the course, in seminar format, concerns recently published studies found in the peer-reviewed literature. Students also participate in a class project to design and execute a restoration plan for a location on campus.
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4.00 Credits
This course provides additional and independent laboratory experience for students enrolled in Chemistry 142. Students choose their own projects. Past favorites include synthesis and analysis of aspirin; tracing a historical controversy in inorganic chemistry through synthesis and analysis of a series of cobalt compounds; studies of cis-trans and optical isomerism; and diverse analyses (sodas, fruit juices, aluminum cans, antacids, vitamins, milk, alcohol, water, cigarettes, car exhaust, and cigarette smoke). A time commitment of one afternoon per week is expected.
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4.00 Credits
An introduction to the composition, structure, and properties of matter. The first semester covers atomic structure, stoichiometry, periodic trends, bonding and molecular geometry, thermochemistry, and the behavior of gases, liquids, and solids. Central concepts in the second semester are energy transfer, spontaneity, and change (thermochemistry, chemical equilibrium, and kinetics). The laboratory stresses basic techniques and quantitative applications. Basic algebra skills are required. Concurrent enrollment in calculus is recommended for students who intend to concentrate in chemistry.
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4.00 Credits
Students study the structure and reactions of specific types of organic compounds and develop interrelationships that provide an integrated understanding of organic chemistry. The course emphasizes general principles and reaction mechanisms, but students are also expected to accumulate and utilize factual material. The laboratory is coordinated with classroom topics and should provide direct experience with many reactions and concepts. The laboratory is also intended to develop familiarity with experiment design, experimental techniques, and instrumental methods such as chromatography and spectroscopy. Prerequisite: Chemistry 141-142.
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4.00 Credits
A survey of the field of analytical chemistry, with emphasis on the basic principles of solution equilibriums. Quantitative treatment of solubility, acidity, and oxidation potential provides the background for understanding gravimetric and volumetric techniques. Modern methods of instrumental analysis are studied and integrated into the laboratory work. Prerequisite: Chemistry 141-142.
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4.00 Credits
An introduction to the chemistry of the elements, this course places emphasis on the classification of the properties and reactivity of the elements by chemical periodicity, structure, and bonding. Topics in modern inorganic chemistry include coordination chemistry of the transition metals, organometallic chemistry, and bioinorganic chemistry. Laboratory work includes synthetic and instrumental techniques that apply to inorganic and organometallic chemistry. Prerequisites: Chemistry 201-202; either Chemistry 301 or Chemistry 411-412.
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4.00 Credits
An introduction to the theory and use of molecular orbital calculations. Huckel calculations are stressed, and results are applied to the study of the structure and reactivity of organic molecules. Particular attention is paid to orbital symmetry and frontier orbital theory. Depending upon student interests, advanced calculations may also be considered. Other advanced topics may include electronic spectroscopy, photochemistry, and molecular mechanics. Prerequisites: Chemistry 201-202 and Physics 141 and 142.
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4.00 Credits
An introduction to the design and development of organic syntheses. The starting point is the predictable design of organic structures by the "disconnection approach," based heavily onthe use of carbanions and other modern reactions. The versatility of these methods is discussed, using novel ways to apply these reactions to generate elusive structures. Fairly complicated syntheses are evaluated to appreciate new ideas and approaches to synthesis. Recent papers in organic synthesis are presented by the professor, participating students, and visiting speakers. Performance is evaluated on the basis of seminar participation and presentation. Prerequisite: Chemistry 201-202.
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