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Course Criteria
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3.00 Credits
3 hours lecture per week Prerequisite(s): BIOL 130 or ZOOL 141. Recommended Preparation: CHEM 151 or CHEM 161. MICR 135 is an introduction to the study of microorganisms, host parasite relationships, the control and the characterization of disease-causing organisms. Upon successful completion of MICR 135, the student should be able to: Describe morphology, growth and metabolism in bacteria. Identify principles of host-parasite relationships. Describe principles and methods of control of microorganisms. Describe the principles and actions of antibiotics. Describe specimen collection and handling. Describe the structure and chemistry of immunoglobulins. Discuss the mechanisms that protect the body from disease and/or injury. 7
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2.00 Credits
4 hours lecture/lab per week Prerequisite(s): Credit or concurrent enrollment in MICR 130 or credit or concurrent enrollment in MICR 135. Recommended Preparation: MATH 25. MICR 140 covers the fundamental laboratory aspects of microbiology with a public health and medical emphasis. Upon successful completion of MICR 140, the student should be able to: Use the metric system and scientific notation. Use and properly care for the compound microscope, including the oil immersion lens. Prepare, examine and accurately interpret various stained slide specimens including gram stained, capsule stained, endospore stained and flagella stained specimens. Understand and properly execute the aseptic transfer of bacterial cultures. Use sterile pipettes aseptically and accurately. Demonstrate the ubiquity of microbes as part of our normal flora and as present in the environment. Understand and demonstrate the principles and the techniques which are used to control microorganisms such as antibiotics, food preservatives and the chemical and physical disinfecting and sterilizing agents. Enumerate the bacteria in food and water samples and mathematically predict the growth characteristics of these bacteria. Understand and demonstrate the effect of different personal hygiene practices on our normal flora and on pathogens. Demonstrate and understand the various nutritional requirements and characteristics of medically important bacteria. Demonstrate the ability to isolate, in pure culture, and to identify common human commensal bacteria. Demonstrate the principles involved in the transmission of pathogenic organisms by the common routes. Demonstrate the thinking skills needed to critically observe, measure, evaluate and interpret experimental data and the creativity needed to formulate hypotheses to explain the data.
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2.00 Credits
4 hours lecture/lab per week Prerequisite(s): Credit or concurrent enrollment in MICR 130, MICR 135 or BIOL 171; credit or concurrent enrollment in MICR 140, MLT 107 or BIOL 171L; credit or concurrent enrollment in CHEM 151 or higher level chemistry course; credit or concurrent enrollment in CHEM 151L or higher level chemistry course. MICR 161 lecture/laboratory course covers the fundamental aspects of both immunology and protein chemistry as it is performed in clinical and biotechnology laboratories. Upon successful completion of MICR 161, the student should be able to: Describe the structure and chemistry of proteins, with especial emphasis on the immunoglobulins. Describe and explain the principles underlying antigenantibody reactions. Demonstrate proficiency in performing a variety of immunoassays including agglutination, precipitation, ELISA, and fluorescent antibody procedures. Explain the principles of electrophoresis and perform polyacrylamide gel electrophoresis and western blotting. Explain the principles and perform fundamental protein fractionation, separation and purification techniques such as salt fractionation, size exclusion chromatography and ion exchange chromatography. Describe the principles underlying immunization strategies particularly as they relate to the production of monoclonal antibodies. Describe the principles involved in developing screening assays for monoclonal antibody production; then, coat plates with candidate antigens and perform the assays. 8
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3.00 Credits
6 hours lecture/lab per week Prerequisite(s): MICR 130, MICR 135 or BIOL 171; MICR 140, MLT 107 or BIOL 171L; CHEM 151 or higher; CHEM 151L or higher. MICR 230 covers the fundamental theoretical and laboratory aspects of molecular biology. The basic principles which govern the structure and function of proteins, nucleic acids and macromolecular complexes will be studied. Students will learn and become proficient at performing the fundamental laboratory procedures of biotechnology. Upon successful completion of MICR 230, the student should be able to: Describe the structure of proteins, nucleic acids and macromolecular complexes. Describe the function of nucleic acids, proteins and macromolecules in DNA replication, transcription, translation, mutagenesis and DNA repair. Describe the regulation of gene activity in prokaryotes and eukaryotes. Describe basic principles and techniques of molecular biology including the use of plasmids and transposons to generate recombinant DNA. Prepare, sterilize and dispense the basic types of media used for the cultivation of bacteria. Operate all the basic equipment of a molecular biology laboratory, including but not limited to large autoclaves and bench top autoclaves, water distillation apparatus, biological safety cabinets, spectrophotometers and ELISA readers, electrophoresis equipment, centrifuges and microcentrifuges. Perform agarose gel electrophoresis. Isolate and quantitate chromosomal and plasmid DNA from bacteria. Perform and analyze restriction enzyme digestions of DNA. Prepare and screen a genomic library. Prepare enzyme labeled probes and perform southern blots. Perform polymerase chain reactions under a variety of conditions. Analyze DNA and amino acid sequence data by searching sequence data bases.
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2.00 Credits
4 hours lecture/lab per week Prerequisite(s): MICR 130 or MICR 135 or BIOL 171; MICR 140 or MLT 107 or BIOL 171L; CHEM 151/151L or higher level chemistry course with lab; or instructor's consent. Comment: MICR 240 is cross-listed as BIOL 275L. MICR 240 is a lecture/laboratory course that covers cell biology and the essential principles important to the cultivation and study of cells in tissue culture. Through lectures and laboratory experiments students will acquire a fundamental understanding of the biochemistry and molecular biology of the cell. Students will also acquire competence in tissue culture and experience with modern advances in biotechnology and recombinant DNA technology. Upon successful completion of MICR 240 the student should be able to: Prepare media and buffers needed for the culture of animal, plant and microalgae cells. Demonstrate proficiency in the specialized sterilization and quality control procedures used in a tissue culture laboratory. Demonstrate proficiency in routine cell culture protocols such as feeding schedules and medium supplements, subcultivation procedures, cell enumeration and viability testing, cryopreservation, and the detection and disposition of contaminated cultures. Demonstrate knowledge of the basic principles of protein chemistry by applying these principles in the designing and reporting of experiments utilizing enzymatic reactions, electrophoresis and immunoassays. Demonstrate knowledge of the basic principles of DNA structure, function, and chemistry by applying these principles in the designing and reporting of experiments utilizing DNA extraction and purification, electrophoresis, restriction enzyme analysis, DNA amplification, sequencing, and sequence analysis using standard bioinformatics databases and analysis protocols. Describe in detail the organization of life at the cellular and subcellular levels. 9 Describe the structure and function of biological membranes and demonstrate an understanding of the processes which occur at the cell surface. Describe in detailed and specific terms the fundamental catabolic and anabolic metabolic processes that occur at the cellular level. Describe and experimentally manipulate the cytoskeleton particularly as it relates to intracellular traffic, cytokinesis and cell motility. Describe and experimentally manipulate the basic processes involved in cell signaling and the cell cycle and define the role of these processes in cell differentiation and in cancer. Describe the theories explaining the development of eukaryotes and the evolution of multicellular organisms. Describe and debate the ethical issues surrounding existing and proposed research and applications using living cells.
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12.00 Credits
8 hours lecture, 4 hours lecture/lab, 6 hours lab per week Prerequisite(s): Acceptance into MICT program; completion of a State of Hawai'i approved Emergency Medical Technician program; State licensure at the EMT level. Comment: Letter grade only. MICT 150 may not be audited. MICT 150 may not be taken credit/no credit. Students are required to have a laptop computer. MICT 150 is the theory and laboratory practice of advanced life support knowledge and skills used in the assessment and treatment of adult and pediatric patients with medical and trauma conditions requiring pre-hospital emergency care. Upon successful completion of MICT 150, the student should be able to: Improve knowledge and skills obtained at the EMT level to refine patient assessment, including taking the patient's history and performing a physical examination to assess illness or degree of injury in a multicultural environment. Safely and accurately administer medications. Explain and demonstrate the initiation and continuation of advanced life support care under medical control, including recognition of presenting symptoms and initiation of appropriate invasive and non-invasive treatment for surgical, medical, pediatric, obstetric and psychiatric emergencies, and airway and respiratory problems. Safely and accurately perform in a non-patient care situation including designated advanced life support measures.
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5.00 Credits
8 hours lecture, 6 hours lab per week for 8 weeks Prerequisite(s): A grade of "C" or higher in MICT 150; acceptance into MICT program; completion of a State of Hawai'i approved Emergency Medical Technician program; State licensure at the EMT level.Comment: Letter grade only. MICT 160 may not be audited. MICT 160 may not be taken credit/no credit. MICT 160 is the theory and laboratory practice of advanced life support skills in assessment and treatment of patients with cardiac conditions that require pre-hospital emergency care. Upon successful completion of MICT 160, the student should be able to: Describe detailed anatomy and physiology of the cardiovascular systems. Recognize normal and abnormal cardiac rhythms, including life threatening arrhythmias and relate to cardiac output. Recognize and interpret normal and abnormal 12-lead EKG's and correlate its clinical relevance. Describe specific treatment of arrhythmias 0 according to approved standing orders for Hawaii's MICTs. Perform advanced cardiac life support skills.
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5.00 Credits
6 hours lecture, 4.5 hours lab per week for 10 weeks Prerequisite(s): A grade of "C" or higher in MICT 160; acceptance into MICT program; completion of a State of Hawai'i approved Emergency Medical Technician program; State licensure at the EMT level.Comment: Letter grade only. MICT 200 may not be audited. MICT 200 may not be taken credit/no credit. ACLS, PALS, AMLS and PHTLS WRITTEN must be passed at 84% in order to complete MICT 200. MICT 200 is the theory and laboratory practice of additional advanced medical, trauma, cardiac life support in the pre-hospital emergency environment. Upon successful completion of MICT 200, the student should be able to: Complete the Pediatric Advanced Life Support and the Advanced Cardiac Life Support-Provider courses according to standards set by the American Heart Association. Complete the Advanced Medical Life Support and Pre-Hospital Trauma Life Support-Provider courses according to standards set by the National Association of Emergency Medical Technicians. Recognize signs and symptoms, and perform medical management of various types of burns and chemical, biological, nuclear, radiological and environmental emergencies in the pre-hospital environment. Perform, in the non-patient care situation, all skills required for functioning as a Mobile Intensive Care Technician (MICT).
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4.00 Credits
18 hours clinical experience per week for 10 weeks Prerequisite(s): A grade of "C" or higher in MICT 200; acceptance into MICT Program; completion of a State of Hawai'i approved Emergency Medical Technician program; State licensure at the EMT level.Comment: Mandatory credit/no credit grading. MICT 201 may not be audited. MICT 201 may not be taken for a letter grade. A student must earn a PASS on all evaluations by clinical preceptors in order to pass the course. MICT 201 provides an opportunity for participation in basic and advanced life support skills for patients in selected clinical facilities, includes major hospitals and ambulances. Each student is assigned one on one with a preceptor. Upon successful completion of MICT 201, the student should be able to: Safely and accurately perform basic and advanced life support procedures, under direct supervision in a hospital or ambulance setting. Correlate the clinical and theoretical aspects of selected patient situations through a series of case reports.
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4.00 Credits
1 hour lecture, 39 hours ambulance internship per week for 4 weeks Prerequisite(s): A grade of "C" or higher in MICT 200; a grade of "C" or higher in MICT 201; acceptance into MICT Program; completion of a State of Hawai'i approved Emergency Medical Technician program; State licensure at the EMT levComment: Mandatory credit/no credit grading. MICT 202 may not be audited. MICT 202 may not be taken for a letter grade. MICT 202 provides the initial experience as a MICT intern on an advanced life support emergency ambulance. MICT 202 includes rotation one of the 1 required five rotations. Each student is assigned one on one with a preceptor. Upon successful completion of MICT 202, the student should be able to: Safely and accurately perform in the emergency situation, at an introductory level, all advanced life support procedures as listed in the Board of Medical ExaminersRules for Emergency Ambulance Personnel. Exercise personal judgment in case of interruption in medical direction caused by communication failure or in cases of immediate life threatening conditions; provide such emergency care as has been specifically authorized by approved standing orders.
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