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CHEM 251: Principles of Organic Chemistry I
1.00 Credits
Wesleyan University
This course offers an introduction to the chemistry of carbon compounds with emphasis on the relationship between structure and reactivity. The laboratory course CHEM257 is normally elected concurrently but is not required.
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CHEM 251 - Principles of Organic Chemistry I
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CHEM 257: General Chemistry Laboratory
0.50 Credits
Wesleyan University
Normally taken along with CHEM251, this course provides laboratory work in quantitative chemical procedures and introductory chemical laboratory practices. This course is required by most medical, dental, and veterinary schools and is a prerequisite for CHEM258.
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CHEM 257 - General Chemistry Laboratory
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CHEM 307: Molecular Biophysics Journal Club I
0.50 Credits
Wesleyan University
This course includes presentation and active discussion of a series of current research articles in the field of molecular biophysics and biophysical chemistry from the BIOPHYSICAL JOURNAL, BIOPOLYMERS, CURRENT OPINION IN STRUCTURAL BIOLOGY, JOURNAL OF BIOMOLECULAR STRUCTURE AND DYNAMICS, AND THE ANNUAL REVIEW OF MOLECULAR BIOPHYSICS AND BIOMOLECULAR STRUCTURE.
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CHEM 307 - Molecular Biophysics Journal Club I
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CHEM 325: Introduction to Biomolecular Structure
1.00 Credits
Wesleyan University
This course aims to provide a framework for understanding three-dimensional structures of proteins, nucleic acids, and their complexes. The first half of the course emphasizes structural modules and topological patterns in major classes of proteins and nucleic acids. The second part of the course covers novel structural motifs, such as helix-turn-helix, zinc-finger, and leucine zipper, that are responsible for recognition of specific nucleotide sequences in nucleic acids by proteins. Analysis of structures using tools available on the Web and independent exploration of protein and nucleic acid databases are strongly encouraged.
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CHEM 325 - Introduction to Biomolecular Structure
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CHEM 337: Physical Chemistry I: Quantum Mechanics and Spectroscopy
1.00 Credits
Wesleyan University
This course is a rigorous introduction to quantum mechanics. The course covers wave mechanics, operator methods, matrix mechanics, perturbation theory, angular momentum, molecular vibrations, atomic and molecular structure, symmetry, and spectroscopy.
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CHEM 337 - Physical Chemistry I: Quantum Mechanics and Spectroscopy
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CHEM 359: Advanced Organic Synthesis
1.00 Credits
Wesleyan University
The control of reactivity and selectivity to achieve specific syntheses is one of the overarching goals of organic chemistry. This course is intended to provide the advanced undergraduate and graduate students in chemistry with a sufficient foundation to comprehend and use the research literature in organic chemistry. Concentrating on the most important reactions and efficient synthetic methods used for organic synthesis, this course presents the material by reaction type. The planning and execution of multistep synthesis will also be included.
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CHEM 359 - Advanced Organic Synthesis
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CHEM 375: Integrated Chemistry Laboratory I
1.00 Credits
Wesleyan University
An advanced laboratory course in chemistry involving work from the major subdisciplines: organic, inorganic, biochemistry, physical, and instrumental. Emphasis will be placed on integrating aspects of chemical synthesis, spectroscopic characterization, and determination of physical properties in each exercise.
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CHEM 375 - Integrated Chemistry Laboratory I
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CHEM 382: Practical NMR
1.00 Credits
Wesleyan University
This course will cover how a spectrometer works as well as the theory and application of NMR experiments. The topics will include one-dimensional proton and heteronuclear experiments as well as decoupling. The course will begin with how the spectrometer works and how data processing is carried out, as well as how to calibrate the spectrometer and shim the magnet. The one-dimensional TOCSY and NOESY experiments will then be covered. The course will also cover heteronuclear and homonuclear two-dimensional NMR experiments. The experiments will include two-dimensional DQFCOSY, TOCSY, NOESY, and ROESY proton experiments as well as heteronuclear experiments to correlate the chemical shifts of protons and heteronuclei, as well as how to select heteronuclear resonances on the basis of the number of directly attached protons. The course will consist of lectures as well as a laboratory component in which the Mercury 300 will be used to obtain data that will be analyzed using the methods developed in the lecture part of the course. This course is specifically aimed at the general users of the Mercury spectrometer who wish to learn how to carry out and analyze advanced one-dimensional as well as two-dimensional NMR experiments.
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CHEM 382 - Practical NMR
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CHEM 383: Biochemistry
1.00 Credits
Wesleyan University
This introductory course to the principles and concepts of contemporary biochemistry presents both the biological and chemical perspectives. The major themes will be the structure of proteins and the basis of enzymatic activity, cellular metabolism and the generation and storage of metabolic energy, and general principles of the biosynthesis of cellular components.
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CHEM 383 - Biochemistry
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CHEM 387: Enzyme Mechanisms
0.50 Credits
Wesleyan University
The chemical mechanisms involved in the action of a series of typical enzymes will be considered.
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CHEM 387 - Enzyme Mechanisms
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