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Course Criteria
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3.00 Credits
Learning molecular and cell biology experimental design and approaches through independent research projects. Students, working in pairs, will explore the research process and gain extensive first-hand experience in: hypothesis formation; experimental design; solution preparation and experimental methodology; proposal presentation and defense (oral and written); formal presentation of results and conclusions (oral and written in a publication-style format); the publication process; critical reading and evaluation of primary scientific literature. Prereq., MCDB 1150 or equivalent and instructor consent. Recommended coreq., MCDB 3500.
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3.00 Credits
Covers basic mechanisms for imaging and recent advances used in current biological research, elements of electron optics, image optimization, resolution, radiation damage, various imaging modes (TEM, HVEM, SEM, STEM, STM), specimen quantitation and reconstruction (stereo and 3-D), microanalysis, and electron diffraction. Specimen preparation treated only incidentally. Prereq., one of the following: MCDB 1150, EBIO 1220, MCDB 4500, PHYS 1120, or 2020, or instructor consent. Same as MCDB 5130 and PHYS 4130.
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3.00 Credits
Introduces some of the frontiers in experimental plant research with applications in modern biotechnology, including genetics, hormonal control of growth, stress responses (heat, water, salt), host-pathogen systems (bacteria, fungi, viruses, viroids), plant defense mechanisms, plant cell tissue culture, and genetic engineering of plants. Prereqs., MCDB 3120 and 3500, or instructor consent. Same as MCDB 5140. Approved for arts and sciences core curriculum: critical thinking.
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3.00 Credits
Emphasizes cellular and molecular mechanisms by which organisms protect themselves from pathogens and the experimental basis for our understanding of these processes. Discusses development, function, and misfunction of t-cells, b-cells and other components of the immune system, focusing on the human immune system. Prereqs., MCDB 3120, 3500.
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3.00 Credits
Explores molecular and cellular interactions between bacteria and their eukaryotic hosts that precipitate disease. Activities include critical reading of review and research articles, preparation of homework assignments based on readings, and student presentations of assigned papers. Prereqs., MCDB 2150, 3120, and 3500. Same as MCDB 5330. Approved for arts and sciences core curriculum: critical thinking.
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3.00 Credits
Provides a molecular phylogeny-based perspective on microbial diversity and the interactions between organisms that result in the biosphere. Provides overview of recent methods and findings in microbial ecology, as well as computer-based workshop in molecular phylogeny. Prereqs., CHEM 1131 or 1171, general biology, or instructor consent. Recommended prereqs., EBIO 3400 and/or CHEM 3311. Same as MCDB 5350.
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3.00 Credits
Studies the human organism as a genetic system, including effect of mutation on protein structure and function, biochemical basis of human genetic disease, polymorphic gene loci, gene mapping and identification, gene cloning and characterization, and impact of human genetics on medicine and society. Prereq., MCDB 3500. Approved for arts and sciences core curriculum: critical thinking.
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3.00 Credits
Introduces several cell signaling processes and their biological functions. Students read and analyze original research articles to learn the thinking processes of scientific research. Writing assignments and oral presentations are required. Prereqs., MCDB 3120, 3500, and CHEM 4711, or instructor consent. Same as MCDB 5426. Approved for arts and sciences core curriculum: critical thinking.
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3.00 Credits
Explores the cellular basis of disease. Discusses diseases arising from defects in intracellular targeting, cytoskeletal function, intracellular signaling, genomic instability, gene regulation, cell proliferation, and cell death. Involves student-organized presentations and classroom discussion. Prereq., MCDB 2150, 3120, and 3500. Approved for arts and sciences core curriculum: critical thinking.
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3.00 Credits
Focuses on manifestations of regulated gene expression. Studies gene regulation at multiple steps, including transcription, RNA processing, and translation. Is based on critical analysis of primary research papers. Written assignments and oral presentations are required. Prereq., MCDB 3500 or instructor consent. Same as MCDB 5471. Credit not granted for this course and MCDB 4470/5470. Approved for arts and sciences core curriculum: critical thinking.
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