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Chemistry and Biochemistry C 164: Free Radicals in Biology and Medicine
3.00 Credits
University of California-Los Angeles
Lecture, three hours. Enforced requisites: courses 153A and either 153B or 153C, with grades of C- or better. Biochemical reactivity of dioxygen, its role in mitochondrial metabolism, neurodegenerative diseases, apoptosis, and aging. Discussion of radical reactions, how they are harnessed to achieve enzyme catalysis, and how free radicals contribute to or regulate essential biological processes. These same reactions "run amok" under certain types of stress and can contributeto wide variety of diseases, including neurodegenerative diseases (e.g., Huntington's, Parkinson's,and Alzheimer's diseases), mitochondrial diseases, atherosclerosis, and aging. Concurrently scheduled with course C264. P/NP or letter grading.
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Chemistry and Biochemistry C 164 - Free Radicals in Biology and Medicine
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Chemistry and Biochemistry C 165: Metabolic Control by Protein Modification
2.00 Credits
University of California-Los Angeles
First five weeks. Lecture, three hours; discussion, one hour. Requisites: courses 153A, 153B, 153C. Biochemical basis of controlling metabolic pathways by posttranslational modification of proteins, including phosphorylation and methylation reactions. Concurrently scheduled with course C265. Letter grading.
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Chemistry and Biochemistry C 165 - Metabolic Control by Protein Modification
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Chemistry and Biochemistry C 172: Advanced Inorganic Chemistry
4.00 Credits
University of California-Los Angeles
Lecture, three hours; discussion, one hour. Requisite: course 171 with grade of C- or better. Systematic approach to modern inorganic chemistry, structure and bonding of inorganic molecules and solids, structure/reactivity relationships, vibrational spectra of complexes, electronic structure and ligand-field theory, mechanisms of inorganic reactions, bonding and spectroscopy of organometallic compounds, transition metals in catalysis and biology. Concurrently scheduled with course C273. P/NP or letter grading.
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Chemistry and Biochemistry C 172 - Advanced Inorganic Chemistry
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Chemistry and Biochemistry C 174: Inorganic and Metalorganic Laboratory Methods
5.00 Credits
University of California-Los Angeles
Lecture, two hours; laboratory, eight hours. Enforced requisites: courses 30CL and C172, with grades of C- or better. Synthesis of inorganic compounds, including air-sensitive materials; Schlenck techniques; chromatographic and ion exchange methods; spectroscopic characterization and literature applications. Concurrently scheduled with course C274. P/NP or letter grading.
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Chemistry and Biochemistry C 174 - Inorganic and Metalorganic Laboratory Methods
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Chemistry and Biochemistry C 175: Inorganic Reaction Mechanisms
4.00 Credits
University of California-Los Angeles
Lecture, three hours. Requisites: courses 110A, 110B, 113A, C172. Survey of inorganic reactions; mechanistic principles; electronic structure of metal ions; transition-metal coordination chemistry; inner- and outer-sphere and chelate complexes; substitution, isomerization, and racemization reactions; stereochemistry; oxidation/reduction, free/radical, polymerization, and photochemical reactions of inorganic species. May be concurrently scheduled with course C275. P/NP or letter grading.
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Chemistry and Biochemistry C 175 - Inorganic Reaction Mechanisms
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Chemistry and Biochemistry C 176: Group Theory and Applications to Inorganic Chemistry
4.00 Credits
University of California-Los Angeles
Lecture, three hours; discussion, one hour. Requisites: courses 113A, C172. Group theoretical methods; molecular orbital theory; ligandfield theory; electronic spectroscopy; vibrational spectroscopy. May be concurrently scheduled with course C276A. P/NP or letter grading.
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Chemistry and Biochemistry C 176 - Group Theory and Applications to Inorganic Chemistry
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Chemistry and Biochemistry C 179: Biological Inorganic Chemistry
4.00 Credits
University of California-Los Angeles
Lecture, three hours. Requisites: courses 153A (or 153AH), 171. Role of metal ions in biology. Topics include interactions of metal ions with proteins, nucleic acids, and other biological molecules; mechanisms of metal ion transport and storage; introduction to metalloenzyme; metalloproteins in electron transfer, respiration, and photosynthesis; metals in medicine. Concurrently scheduled with course C279. P/NP or letter grading.
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Chemistry and Biochemistry C 179 - Biological Inorganic Chemistry
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Chemistry and Biochemistry C 180: Solid-State Chemistry
4.00 Credits
University of California-Los Angeles
Lecture, three hours. Requisite: course C172. Survey of new materials and methods for their preparation and characterization, with emphasis on band theory and its relationship to chemical, optical, transport, and magnetic properties, leading to deeper understanding of these materials. Concurrently scheduled with course C280. P/NP or letter grading.
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Chemistry and Biochemistry C 180 - Solid-State Chemistry
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Chemistry and Biochemistry C 181: Polymer Chemistry
4.00 Credits
University of California-Los Angeles
Lecture, three hours; discussion, one hour. Requisites: courses 30B, 110A. Synthesis of organic and inorganic macromolecules, thermodynamic and statistical mechanical descriptions of unique properties of polymers, polymer characterization methods, and special topics such as conductive and biomedical polymers and polymeric reagents in synthesis. Concurrently scheduled with course C281. P/NP or letter grading.
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Chemistry and Biochemistry C 181 - Polymer Chemistry
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Chemistry and Biochemistry C 185: Materials Chemistry Laboratory
5.00 Credits
University of California-Los Angeles
Lecture, two hours; laboratory, eight hours. Requisites: courses 30AL, 110A, 113A, 171. Materials synthesis and physical properties of complex materials. Combines synthetic skills with fundamental physical understanding and characterization in approximately equal proportions to relate materials synthesis to materials function. Concurrently scheduled with course C285. Letter grading.
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Chemistry and Biochemistry C 185 - Materials Chemistry Laboratory
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