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Course Criteria
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3.00 Credits
Fall 2008. ANNE E. MCBRIDE. Covers the development of the immune response, the cell biology of the immune system, the nature of antigens, antibodies, B and T cells, and the complement system. The nature of natural immunity, transplantation immunology, and tumor immunology are also considered. Prerequisite: Biology 212, 217, 218, 224, or permission of the instructor.
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3.00 Credits
Spring 2008. NATHANIEL T. WHEELWRIGHT. Advanced study of the biology of birds, including anatomy, physiology, distribution, and systematics, with an emphasis on avian ecology and evolution. Through integrated laboratory sessions, field trips, discussion of the primary literature, and independent research, students learn identification of birds, functional morphology, and research techniques such as experimental design, behavioral observation, and field methods. Optional field trip to the Bowdoin Scientific Station on Kent Island. Prerequisite: Biology 215 or 225.
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3.00 Credits
Every semester. KATHERINE R. FARNHAM AND THE BIOCHEMISTRY PROGRAM. Comprehensive laboratory course in molecular biology and biochemistry that reflects how research is conducted and communicated. Includes sequential weekly experiments, resulting in a cohesive, semester-long research project. Begins with genetic engineering to produce a recombinant protein, continues with its purification, and finishes with functional and structural characterization. Emphasis is on cloning strategy, controlling protein expression, and protein characterization using techniques such as polymerase chain reaction, affinity chromatography, isoelectric focusing and high-performance liquid chromatography. Students also learn to manipulate data using structural and image analysis software. (Same as Chemistry 263.) Prerequisite: Biology 224 or Chemistry 231 (may be taken concurrently).
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3.00 Credits
Spring 2007. HADLEY WILSON HORCH. Examination of the molecular control of neuronal structure and function. Topics include the molecular basis of neuronal excitability, the factors involved in chemical and contactmediated neuronal communication, and the complex molecular control of developing and regenerating nervous systems. Weekly laboratories complement lectures by covering a range of molecular and cellular techniques used in neurobiology and culminate in brief independent projects. A weekend at the Nerve Net Science Meeting is required. Prerequisite: Biology 102, 104 or 109, and one from Biology 212, 213, 224, 253, or Psychology 218.
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3.00 Credits
Fall 2006. BARRY A. LOGAN. Plants can be found growing under remarkably stressful conditions. Even your own backyard poses challenges to plant growth and reproduction. Survival is possible only because of a diverse suite of elegant physiological and morphological adaptations. The physiological ecology of plants from extreme habitats (e.g., tundra, desert, hypersaline) is discussed, along with the responses of plants to environmental factors such as light and temperature. Readings from the primary literature facilitate class discussion. Excursions into the field and laboratory exercises complement class material. (Same as Environmental Studies 280.) Prerequisite: Biology 210.
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3.00 Credits
THE DEPARTMENT.
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3.00 Credits
Spring 2008. WILLIAM L. STEINHART. A study of the viruses of eukaryotes,beginning with lectures on fundamental virology and followed by student-led seminars based on the primary literature. Covers taxonomy, structure, replication, pathogenesis, epidemiology, and public health aspects of viruses. Prerequisite: Biology 212, 218, or permission of instructor.
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3.00 Credits
Fall 2006. ANNE E. MCBRIDE. Seminar exploring the numerous roles of ribonucleic acid, from the discovery of RNA as a cellular messenger to the development of RNAs to treat disease. Topics covered also include: RNA enzymes, interactions of RNA viruses with host cells, RNA tools in biotechnology, and RNA as a potential origin of life. Focuses on discussions of papers from the primary literature. Prerequisite: One from Biology 212, 218, 224, 232, or permission of the instructor.
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3.00 Credits
Spring 2008. BARRY A. LOGAN. Ordinary cellular metabolism in aerobic environments results in the production of free radicals, and free radical-mediated cellular damage underlies many human diseases. In response to the danger they pose, organisms evolved elaborate antioxidant systems that detoxify free radicals. The biology of free radicals and antioxidants in organisms ranging from bacteria to plants to humans is discussed, along with the importance of free radicals in disease processes. Time is devoted to discussing the primary literature and occasional laboratory sessions. Prerequisite: A 200-level (or above) course in biology, or permission of the instructor.
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3.00 Credits
Fall 2006. MICHAEL F. PALOPOLI. The dynamics of evolutionary change at the molecular level are examined. Topics include: neutral theory of molecular evolution, rates and patterns of change in nucleotide sequences and proteins, molecular phylogenetics, and genome evolution. Explores the evolution of development and the application of molecular methods to traditional questions in evolutionary biology. Prerequisite: Biology 212, 216, 217, 218, or 224, or permission of the instructor.
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