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Course Criteria
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2.00 Credits
Student Laboratory course with practical application of selected molecular, biochemical, and immunologic techniques. Designed to provide limited experience with advanced chromatographic techniques (DEAE-cellulose, affinity columns, HPLC, and gas); multiple electrophoresis techniques (starch-gel, SDS-page, Southern blot); nucleic acid analysis and manipulation; ligand production and utilization; cell culture, including appropriate sterilization methods, aseptic handling, and steps to ensure attachment. Prerequisite: Admission to the Clinical Laboratory Sciences program or consent of instructor. LAB
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1.00 Credits
Introduction to analysis of journal articles. Initial sessions will place an emphasis upon reading the article with an eye to replicating a described method or specific technique; analyzing data presented for validity; acceptance or rejection of the researchers' conclusions. Follow-up sessions will involve analyzing and presenting selected articles. Prerequisite: Admission to the Clinical Laboratory Sciences program or consent of instructor. LEC
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1.00 Credits
A lecture course covering the structure of the atom, isotopes, and radioactivity. Emphasis will be on radiation protection and safe handling of isotopes. In addition, the student will be introduced to methods for detection and quantitation of radioactivity in biological materials. Prerequisite: Admission to the Clinical Laboratory Sciences program or consent of instructor. LEC
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4.00 Credits
Placement of the student in a biotechnology core facility supporting molecular biological research from multiple laboratories. Such a core facility would provide, but not to be restricted to, the following methodologies: amino acid analysis; protein/peptide sequencing; peptide synthesis; DNA/RNA sequencing; oligonucleotide synthesis. Prerequisite: Admission to the Clinical Laboratory Sciences program or consent of instructor. LAB
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2.00 Credits
Web based course that provides the student with a targeted review of molecular and cytogenetics techniques, current theory, techniques and applications concerning protein structure and function, current theory, techniques and applications of molecular immunology. Review in each topic is augmented with situation simulations in research and diagnostic applications of the appropriate techniques. Prerequisite: Admission to the Clinical Laboratory Sciences program or consent of the instructor. LEC
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4.00 Credits
Placement of the student in a molecular genetics research laboratory (utilizing either prokaryotic or eucaryotic organisms or both) working with laboratory staff on an on-going small project within the laboratory. Molecular genetics laboratories utilized could be involved in, but not restricted to, any of the following activities: gene sequencing, cloning or splicing: elucidation of the mechanisms that regulate gene expression; proto-oncogene activation. Prerequisite: Admission to the Clinical Laboratory Sciences program or consent of instructor. LAB
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4.00 Credits
Placement of the student in a cytogenetics laboratory. Cytogenetics laboratories utilized would be involved in, but not restricted to, performing cell culture and harvest at metaphase; staining for band identification; FISH. Prerequisite: Admission to the Clinical Laboratory Sciences programs or consent of instructor. LAB
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4.00 Credits
Placement of the student in a protein chemistry laboratory (utilizing either prokaryotic or eucaryotic organisms or both). Laboratories utilized could be involved in, but not restricted to, protein production on a large scale; protein isolation and purification; amino acid sequencing; elucidation of three-dimensional structure; determination of the function(s) of the protein studied. Prerequisite: Admission to the Clinical Laboratory Sciences program or consent of instructor. LAB
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4.00 Credits
Placement of the student in a molecular biology or molecular immunology research laboratory that focuses on cell-to-cell signaling. Laboratories utilized could be involved in, but not restricted to, cytokine/chemokine production and isolation; biochemical characterization of the molecule; elucidation of function. Prerequisite: Admission to the Clinical Laboratory Sciences program or consent of instructor. LAB
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4.00 Credits
Placement of the student in an immunochemistry or cell mediated immunology research laboratory. Laboratories utilized could be involved in, but not restricted to, cytokine/chemokine production and isolation; biochemical characterization of an immune mediator; elucidating the functions(s) of an immune mediator; cell-to-cell communication in regulation of immune function; cellular interactions; HLA phenotypes and risk rate for immune function disease; antigen characterization and vaccine development. Prerequisite: Admission to the Clinical Laboratory Sciences program or consent of instructor. LAB
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