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Bi 9: Cell Biology
9.00 Credits
California Institute of Technology
Continues coverage of biology at the cellular level, begun in Bi 8. Topics: cytoplasmic structure, membrane structure and function, cell motility, and cell-cell recognition. Emphasis on both the ultrastructural and biochemical approaches to these topics. Instructors: Aravin, Deshaies.
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Bi 9 - Cell Biology
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Bi 90 abc: Undergraduate Thesis
1.00 - 9.00 Credits
California Institute of Technology
Intended to extend opportunities for research provided by Bi 22 into a coherent individual research project, carried out under the supervision of a member of the biology faculty. Normally involves three or more consecutive terms of work in the junior and senior years. The student will formulate a research problem based in part on work already carried out, evaluate previously published work in the field, and present new results in a thesis format. First two terms graded pass/fail; final term graded by letter on the basis of the completed thesis. Instructor: Bjorkman.
Prerequisite:
18 units of Bi 22 (or equivalent research experience) in the research area proposed for the thesis, and instructor’s permission.
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Bi 90 abc - Undergraduate Thesis
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BMB 170 abc: Biochemistry and Biophysics of Macromolecules and Molecular Assemblies
9.00 Credits
California Institute of Technology
First term: detailed analysis of the structures of the four classes of biological molecules and the forces that shape them. Introduction to molecular biological and visualization techniques. Second term: basic principles of modern biophysical and structural methods to interrogate macromolecules from the atomic to cellular levels, including X-ray crystallography, NMR spectroscopy, molecular dynamics, electron and light microscopy, AFM, single molecule techniques, and systems biological simulations. Third term: detailed analysis of specific macromolecular machines and systems that illustrate the principles and biophysical methods taught in the first two terms. Instructors: Clemons, Jensen, Shan, Hoelz,staff.
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BMB 170 abc - Biochemistry and Biophysics of Macromolecules and Molecular Assemblies
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BMB 178: Enzyme Kinetics and Mechanisms
9.00 Credits
California Institute of Technology
Discussion of the energetic principles and molecular mechanisms that underlie enzymes’ enormous catalytic proficiency and exquisite specificity. Practical kinetics sections discuss how to infer molecular mechanisms from rate/equilibrium measurements and their application to more complex biological systems, and include steady-state and pre-steady-state kinetics, and kinetics at the single molecule level. Instructor: Shan.
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BMB 178 - Enzyme Kinetics and Mechanisms
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BMB 202 abc: Biochemistry Seminar Course
1.00 Credits
California Institute of Technology
A course that includes a seminar on selected topics from outside faculty on recent advances in biochemistry. Students will participate in the seminar along with a formal discussion section with visiting faculty. Instructor: Clemons.
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BMB 202 abc - Biochemistry Seminar Course
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BMB 251 abc: Current Research in Cellular and Molecular Biology
1.00 Credits
California Institute of Technology
Presentations and discussion of research at Caltech in biology and chemistry. Discussions of responsible conduct of research are included. Instructors: Sternberg, Hay.
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BMB 251 abc - Current Research in Cellular and Molecular Biology
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BMB 278: Fundamentals of Molecular Genetics
9.00 Credits
California Institute of Technology
Principles and mechanisms of DNA repair and replication, transcription and splicing, and protein synthesis. Not offered 2012–13.
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BMB 278 - Fundamentals of Molecular Genetics
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BMB 299: Graduate Research
1.00 - 9.00 Credits
California Institute of Technology
Students may register for research units after consultation with their adviser.
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BMB 299 - Graduate Research
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CDS 101: Design and Analysis of Feedback Systems
6.00 Credits
California Institute of Technology
An introduction to feedback and control in physical, biological, engineering, and information sciences. Basic principles of feedback and its use as a tool for altering the dynamics of systems and managing uncertainty. Key themes throughout the course will include input/output response, modeling and model reduction, linear vs. nonlinear models, and local vs. global behavior. This course is taught concurrently with CDS 110 a, but is intended for students who are interested primarily in the concepts and tools of control theory and not the analytical techniques for design and synthesis of control systems. Instructors: Murray, MacMynowski.
Prerequisite:
Ma 1 and Ma 2 or equivalents.
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CDS 101 - Design and Analysis of Feedback Systems
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CDS 110 ab: Introductory Control Theory
12.00 Credits
California Institute of Technology
An introduction to analysis and design of feedback control systems, including classical control theory in the time and frequency domain. Modeling of physical, biological, and information systems using linear and nonlinear differential equations. Stability and performance of interconnected systems, including use of block diagrams, Bode plots, the Nyquist criterion, and Lyapunov functions. Robustness and uncertainty management in feedback systems through stochastic and deterministic methods. Introductory random processes, Kalman filtering, and norms of signals and systems. The first term of this course is taught concurrently with CDS 101, but includes additional lectures, reading, and homework that is focused on analytical techniques for design and synthesis of control systems. Instructor: Murray, MacMynowski, Burdick.
Prerequisite:
Ma 1 and Ma 2 or equivalents; ACM 95/100 may be taken concurrently.
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CDS 110 ab - Introductory Control Theory
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