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Bi 250 b: Topics in Systems Biology
9.00 Credits
California Institute of Technology
The class will focus on quantitative studies of cellular and developmental systems in biology. It will examine the architecture of specific genetic circuits controlling microbial behaviors and multicellular development in model organisms. The course will approach most topics from both experimental and theoretical/computational perspectives. Specific topics include chemotaxis, multistability and differentiation, biological oscillations, stochastic effects in circuit operation, as well as higher-level circuit properties such as robustness. The course will also consider the organization of transcriptional and protein-protein interaction networks at the genomic scale. Instructor: Elowitz.
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Bi 250 b - Topics in Systems Biology
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Bi 250 c: Topics in Systems Neuroscience
9.00 Credits
California Institute of Technology
The class focuses on quantitative studies of problems in systems neuroscience. Students will study classical work such as Hodgkin and Huxley’s landmark papers on the ionic basis of the action potential, and will move from the study of interacting currents within neurons to the study of systems of interacting neurons. Topics will include lateral inhibition, mechanisms of motion tuning, local learning rules and their consequences for network structure and dynamics, oscillatory dynamics and synchronization across brain circuits, and formation and computational properties of topographic neural maps. The course will combine lectures and discussions, in which students and faculty will examine papers on systems neuroscience, usually combining experimental and theoretical/modeling components. Instructor: Siapas.
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Bi 250 c - Topics in Systems Neuroscience
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Bi 251 abc: Current Research in Cellular and Molecular Biology
1.00 Credits
California Institute of Technology
Presentations and discussion of research at Caltech in biology and chemistry. Discussions of responsible conduct of research are included. Instructors: Sternberg, Hay.
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Bi 251 abc - Current Research in Cellular and Molecular Biology
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Bi 252: Responsible Conduct of Research
4.00 Credits
California Institute of Technology
This lecture and discussion course covers relevant aspects of the responsible conduct of biomedical and biological research. Topics include guidelines and regulations, ethical and moral issues, research misconduct, data management and analysis, research with animal or human subjects, publication, conflicts of interest, mentoring, and professional advancement. This course is required of all trainees supported on the NIH training grants in cellular and molecular biology and neuroscience, and is recommended for other graduate students in biology division labs. Undergraduate students require advance instructor’s permission. Graded pass/fail. Instructors: Meyerowitz, Sternberg, staff.
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Bi 252 - Responsible Conduct of Research
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Bi 255: Topics in Emotion and Social Cognition
9.00 Credits
California Institute of Technology
This course will cover recent findings in the psychology and neurobiology of emotion and social behavior. What role does emotion play in other cognitive processes, such as memory, attention, and decision making? What are the component processes that guide social behavior? To what extent is the processing of social information domain-specific? Readings from the current literature will emphasize functional imaging, psychophysical, and lesion studies in humans. Not offered 2012–13.
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Bi 255 - Topics in Emotion and Social Cognition
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Bi 256: Decision Making
6.00 Credits
California Institute of Technology
This special topics course will examine the neural mechanisms of reward, decision making, and reward-based learning. The course covers the anatomy and physiology of reward and action systems. Special emphasis will be placed on the representation of reward expectation; the interplay between reward, motivation, and attention; and the selection of actions. Links between concepts in economics and the neural mechanisms of decision making will be explored. Data from animal and human studies collected using behavioral, neurophysiological, and functional magnetic resonance techniques will be reviewed. Given in alternate years; not offered 2012–13.
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Bi 256 - Decision Making
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Bi 270: Special Topics in Biology
1.00 - 9.00 Credits
California Institute of Technology
Students may register with permission of the responsible faculty member.
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Bi 270 - Special Topics in Biology
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Bi 286 abc: Special Topics in Computation and Neural Systems
1.00 - 9.00 Credits
California Institute of Technology
Students may register with permission of the responsible faculty member.
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Bi 286 abc - Special Topics in Computation and Neural Systems
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Bi 299: Graduate Research
1.00 - 9.00 Credits
California Institute of Technology
Students may register for research units after consultation with their adviser.
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Bi 299 - Graduate Research
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Bi 8: Introduction to Molecular Biology: Organization and Expression of Genetic Information
9.00 Credits
California Institute of Technology
This course and its sequel, Bi 9, cover biology at the molecular and cellular levels. Bi 8 emphasizes genomic structure and mechanisms involved in the organization and regulated expression of genetic information. The focus is on the ways that the information content of the genome is translated into distinctive, cell type specific patterns of gene expression and protein function, with special attention to the problems of gene regulation in complex multicellular organisms. Assignments will include critical dissections of papers from current research literature and individual oral presentations by students to the class on specific topics. Instructor: Rothenberg.
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Bi 8 - Introduction to Molecular Biology: Organization and Expression of Genetic Information
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