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Bi 150: Introduction to Neuroscience
10.00 Credits
California Institute of Technology
General principles of the function and organization of nervous systems, providing both an overview of the subject and a foundation for advanced courses. Topics include the physical and chemical bases for action potentials, synaptic transmission, and sensory transduction; anatomy; development; sensory and motor pathways; memory and learning at the molecular, cellular, and systems level; and the neuroscience of brain diseases. Instructors: Adolphs, Lester.
Prerequisite:
Bi 8, 9, or instructors’ permission.
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Bi 150 - Introduction to Neuroscience
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Bi 152: Bioengineering Principles and Practice in Cell Physiology
9.00 Credits
California Institute of Technology
This course will explore our current knowledge based on the fundamental properties of nerves and synapses, and present the bioengineering principles and developments that drive new avenues of research in cell physiology. We will present the tools used for making current research measurements, dissect the protocols, equipment, and physics that enable the approaches, and discuss the current limitations that limit performance. Students will be expected to engage in one of the technologies and develop a greater understanding in both written and oral presentations to the class. Areas to be investigated will be drawn from electrophysiology, single channel recording, imaging with indicator dyes, and screening technologies. Not offered 2012–13.
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Bi 152 - Bioengineering Principles and Practice in Cell Physiology
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Bi 156: Molecular Basis of Behavior
9.00 Credits
California Institute of Technology
A lecture and discussion course on the neurobiology of behavior. Topics may include biological clocks, eating behavior, sexual behavior, addiction, mental illness, and neurodegenerative diseases. Given in alternate years; not offered 2012–13.
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Bi 156 - Molecular Basis of Behavior
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Bi 157: Comparative Nervous Systems
9.00 Credits
California Institute of Technology
An introduction to the comparative study of the gross and microscopic structure of nervous systems. Emphasis on the vertebrate nervous system; also, the highly developed central nervous systems found in arthropods and cephalopods. Variation in nervous system structure with function and with behavioral and ecological specializations and the evolution of the vertebrate brain. Instructor: Allman. Given in alternate years; offered 2012–13.
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Bi 157 - Comparative Nervous Systems
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Bi 158: Vertebrate Evolution
9.00 Credits
California Institute of Technology
An integrative approach to the study of vertebrate evolution combining comparative anatomical, behavioral, embryological, genetic, paleontological, and physiological findings. Special emphasis will be given to: (1) the modification of developmental programs in evolution; (2) homeostatic systems for temperature regulation; (3) changes in the life cycle governing longevity and death; (4) the evolution of brain and behavior. Given in alternate years; not offered 2012–13.
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Bi 158 - Vertebrate Evolution
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Bi 162: Cellular and Systems Neuroscience Laboratory
12.00 Credits
California Institute of Technology
A laboratory-based introduction to experimental methods used for electrophysiological studies of the central nervous system. Through the term, students investigate the physiological response properties of neurons in insect and mammalian brains, using extra- and intracellular recording techniques. Students are instructed in all aspects of experimental procedures, including proper surgical techniques, electrode fabrication, stimulus presentation, and computer-based data analysis. Graded pass/fail. Instructor: Staff.
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Bi 162 - Cellular and Systems Neuroscience Laboratory
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Bi 166: Microbial Physiology
9.00 Credits
California Institute of Technology
A course on growth and functions in the prokaryotic cell. Topics covered: growth, transport of small molecules, protein excretion, membrane bioenergetics, energy metabolism, motility, chemotaxis, global regulators, and metabolic integration. Instructor: Leadbetter.
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Bi 166 - Microbial Physiology
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Bi 168: Microbial Metabolic Diversity
9.00 Credits
California Institute of Technology
A course on the metabolic diversity of microorganisms. Basic thermodynamic principles governing energy conservation will be discussed, with emphasis placed on photosynthesis and respiration. Students will be exposed to genetic, genomic, and biochemical techniques that can be used to elucidate the mechanisms of cellular electron transfer underlying these metabolisms. Instructor: Newman.
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Bi 168 - Microbial Metabolic Diversity
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Bi 170 abc: Biochemistry and Biophysics of Macromolecules and Molecular Assemblies
9.00 Credits
California Institute of Technology
First term: detailed analysis of the structures of the four classes of biological molecules and the forces that shape them. Introduction to molecular biological and visualization techniques. Second term: basic principles of modern biophysical and structural methods to interrogate macromolecules from the atomic to cellular levels, including X-ray crystallography, NMR spectroscopy, molecular dynamics, electron and light microscopy, AFM, single molecule techniques, and systems biological simulations. Third term: detailed analysis of specific macromolecular machines and systems that illustrate the principles and biophysical methods taught in the first two terms. Instructors: Clemons, Jensen, Shan, Hoelz,staff.
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Bi 170 abc - Biochemistry and Biophysics of Macromolecules and Molecular Assemblies
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Bi 176: Cognition
12.00 Credits
California Institute of Technology
The cornerstone of current progress in understanding the mind, the brain, and the relationship between the two is the study of human and animal cognition. This course will provide an in-depth survey and analysis of behavioral observations, theoretical accounts, computational models, patient data, electrophysiological studies, and brain-imaging results on mental capacities such as attention, memory, emotion, object representation, language, and cognitive development. Instructor: Shimojo; offered 2012–13.
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Bi 176 - Cognition
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