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  • 9.00 Credits

    Survey of the formation of the elements in the universe as a function of cosmic time. Review of the determination of abundances in meteorites, stars, H II regions, and in interstellar and intergalactic gas using the electromagnetic spectrum from radio waves to X rays. Theory of nucleosynthesis in stars, supernovae and the Big Bang, including the s- and r-processes and explosive nucleosynthesis. Particular attention will be paid to the theory and observation of element synthesis in the “First Stars” in the universe. Emphasis will be placed on the connection between element synthesis, the initial mass function of star formation, and galactic evolution, including the role of galactic winds. Not offered 2012–13. Prerequisite:    Ay 121, 123, 124, 126.
  • 3.00 Credits

    Weekly seminar open to declared Ay majors at the discretion of the instructor; nonmajors who have taken astronomy courses may be admitted. Course is intended for sophomores and juniors. This seminar is held in faculty homes in the evening and is designed to encourage student communication skills as they are introduced to faculty members and their research. Each week a student will review a popular-level article in astronomy for the class. Graded pass/fail. Instructor: Readhead.
  • 3.00 Credits

    This course is intended to provide practical experience in the types of writing expected of professional astronomers. Example styles include research proposals, topical reviews, professional journal manuscripts, and articles for popular magazines such as Astronomy or Sky and Telescope. Each student will adopt one of these formats in consultation with the course instructor and write an original piece. An outline and several drafts reviewed by both a faculty mentor familiar with the topic and the course instructor are required. This course is most suitable for juniors and seniors. Fulfills the Institute scientific writing requirement. Instructor: Hillenbrand.
  • 6.00 Credits

    The course covers the process of star formation from both observational and theoretical perspectives. Topics include star-forming regions, physical processes in molecular clouds, core collapse and protostars, premain sequence stars, the impact of star formation upon environment, theoretical evolutionary models, primordial accretion disks, formation of planetary systems, circumstellar debris disks, star formation on galactic scales. Not offered 2012–13.
  • 1.00 - 3.00 Credits

    Course is intended for students with a definite independent reading plan or who attend regular (biweekly) research and literature discussion groups. Instructor’s permission required. Graded pass/fail. Instructor: Staff.
  • 9.00 Credits

    Previous SURF or independent study work can be useful experience. Course is open to senior astronomy majors only. Research must be supervised by a faculty member. Students wishing assistance in finding an adviser and/or a topic for a senior thesis are invited to consult with the astronomy option representative. The student will work with an advisor to formulate a research project, conduct original research, present new results, and evaluate them in the context of previously published work in the field. The first two terms are graded pass/fail and the grades are then changed at the end of the course to the appropriate letter grade for all three terms. In order to receive a passing grade for second term, a work plan and a preliminary thesis outline must be submitted. The written thesis of 20–100 pages must be completed and approved by the adviser and the option representative before the end of the third term. Instructor: Staff.
  • 1.00 Credits

    A weekly seminar series by Caltech faculty providing an introduction to research directions in the field of bioengineering. Graded pass/fail. Instructor: Pierce.
  • 9.00 Credits

    Lectures and experiments demonstrating the bulk and surface properties of materials; review of the major classes of materials—metals, ceramics, polymers—with a view to their relevance to the biomedical field. Special materials and processes of relevance will also be discussed, e.g., hydrogels, fabrics, thin films, bioresorbable and bioerodible materials, cardiac jelly, etc. Proteins, cells, tissues and their interactions with materials; key concepts in reactions between host materials and implants, including inflammation, coagulation, and tumorigenesis. Testing and degradation of biomaterials, material applications in medicine and dentistry, especially orthopedic, cardiovascular, ophthalmologic, oral and maxillofacial implants, and artificial organs. Instructor: Ravi. Prerequisite:    Ph 2 ab or Ph 12 abc, Ch 1 ab, Ch 3 a, or instructor’s permission. MS 115 ab recommended.
  • 9.00 Credits

    Quantitative studies of cellular and developmental systems in biology, including the architecture of specific genetic circuits controlling microbial behaviors and multicellular development in model organisms. Specific topics include chemotaxis, multistability and differentiation, biological oscillations, stochastic effects in circuit operation, as well as higher-level circuit properties such as robustness. Organization of transcriptional and protein-protein interaction networks at the genomic scale. Topics are approached from experimental, theoretical and computational perspectives. Instructors: Elowitz, Murray.
  • 9.00 Credits

    This course will explore the bioengineering principles and developments that drive new avenues of research in molecular biology. We will review the basic principles of current research approaches, dissect the protocols, equipment and chemistry that enable these approaches, and discuss how they impose the existing limitations on performance. Students will be expected to engage in more reading on one of the approaches and develop strategies for implementing improvements. A written and oral presentation of the area under study will be required. Areas to be investigated will be drawn from DNA sequencing, RNA analysis, genomic approaches, flow cytometry, and array technologies. Instructor: Lansford.
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