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Course Criteria
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3.00 Credits
Prerequisite: 360 and permission of department. Distribution: None Semester: Spring Unit: 1.0
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3.00 Credits
Reisberg Topic for 2009-10: Understanding Drugs. A study of a wide variety of drugs, both legal and illegal. The focus will be on how these molecules affect our minds and bodies based on an understanding of their biochemistry. Topics will include antibiotics, steroids, stimulants, intoxicants, narcotics, and hallucinogens. The history, discovery, development, testing, regulation and prohibition of these substances will also be considered. The laboratory will include synthesis and analysis of an analgesic and an intoxicant, plus the detection of drugs in our bodies and on currency. Prerequisite: Open to all students except those who have taken any other chemistry course. Distribution: Natural and Physical Science Semester: Spring Unit: 1.25
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3.00 Credits
Staff This course is designed for students majoring in the physical and biological sciences as well as those wishing an introduction to modern molecular science. Core principles and applications of chemistry are combined to provide students with a conceptual understanding of chemistry that will help them in both their professional and everyday lives. Topics include principles of nuclear chemistry, atomic and mole-cular structure, molecular energetics, chemical equilibrium, and chemical kinetics. The laboratory work introduces students to synthesis and structural determination by infrared and other spectroscopic techniques, periodic properties, computational chemistry, statistical analy-sis and various quantitative methods of analysis. Prerequisite: One year of high school chemistry is strongly recommended. Chemistry 105 is designed for students who have completed high school chemistry and ma-thematics equivalent to two years of algebra. Students must have fulfilled the basic skills component of the Quantitative Reasoning requirement. Students who have questions about their chemistry preparation should consult the department chair. Students who have AP or IB credit in Chemistry, and who elect CHEM 105, forfeit the AP or IB credit. Distribution: Natural and Physical Science or Mathematical Modeling Semester: Fall, Spring Unit: 1.25
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1.00 Credits
Kolodny A one-semester course for students who have completed more than one year of high school chemistry, replacing CHEM 105 and 205 as a prerequisite for more advanced chemistry courses. It presents the topics of nuclear chemistry, atomic structure and bonding, periodicity, kinetics, thermodynamics, electrochemistry, equilibrium, acid/base chemistry, solubility and transition metal chemistry. All of these topics are presented in the context of both historical and contemporary applications. The laboratory includes experiments directly related to topics covered in lecture, an introduction of statistical analysis of data, molecular modeling and computational chemistry, instrumental and clas-sical methods of analysis, thermochemistry and solution equilibria. The course meets for four periods of lecture/discussion and one 3.5 hour laboratory. Prerequisite: Open to students who have a score of 5 on the Chemistry AP exam or an IB score of 5 or above; open also to students with two years of chemistry but without the requisite AP or IB score who perform sufficiently well on the Chemistry 120 Placement Exam. Students must have fulfilled the basic skills component of the Quantitative Reasoning requirement. Not open to students who have completed 105 and/or 205. Students who have AP or IB credit in Chemistry, and who elect CHEM 120, forfeit the AP or IB credit. Distribution: Natural and Physical Science or Mathematical Modeling. Fulfills the Quantitative Reasoning overlay course requirement. Semester: Fall Unit: 1.25
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3.00 Credits
Staff This course builds on the principles introduced in CHEM 105, with an emphasis on chemical equilibrium and analysis, and their role in the chemistry of the environment. Topics include chemical reactions in aqueous solution with particular emphasis on acids and bases, solubili-ty and complexation, electrochemistry, atmospheric chemistry, photochemistry and smog, global warming and acid deposition, sampling and separations, modeling of complex equilibrium and kinetic systems, statistical analysis of data, and solid state chemistry of ceramics, zeolites and new novel materials. The laboratory work includes additional experience with instrumental and noninstrumental methods of analysis, sampling, computational chemistry and solution equilibria. Prerequisites: 105 and fulfillment of the basic skills component of the Quantitative Reasoning requirement. Not open to students who have taken 120. Distribution: Mathematical Modeling or Natural and Physical Science. Fulfills the Quantitative Reasoning overlay course requirement. Semester: Fall, Spring Unit: 1.25
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3.00 Credits
Staff Topics covered include: stereochemistry, synthesis and reactions of alkanes, alkenes, alkynes, alkyl halides, alcohols and ethers, nomen-clature of organic functional groups, IR, and GC/MS. Prerequisite: 105, or 120 or permission of the department. Distribution: Natural and Physical Science Semester: Fall, Spring Unit: 1.25
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3.00 Credits
Staff A continuation of CHEM 211. Includes NMR spectroscopy, synthesis, reactions of aromatic and carbonyl compounds, amines, and carbo-hydrates. In addition, students are expected to study the chemical literature and write a short chemistry review paper. Prerequisite: 211 Distribution: Natural and Physical Science Semester: Fall, Spring Unit: 1.25
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3.00 Credits
Elmore A study of the chemistry of biomolecules and macromolecular assemblies with emphasis on the structure of proteins, nucleic acids, carbo-hydrates, and lipids, as well as methodologies for studying them. This course is the first half of a year-long course sequence in biochemi-stry that continues with CHEM 328. Students who only intend to take a single semester of biochemistry should enroll in CHEM 222. Prerequisite: 205, 211 and BISC 220; or 120, 211 and BISC 220 Distribution: Natural and Physical Science Semester: Fall Unit: 1.25
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3.00 Credits
Elmore A study of the chemistry of biomolecules and macromolecular assemblies, with emphasis on structure-function relationships; an introduc-tion to bioenergetics, enzyme kinetics, and metabolism. This course is intended for students who plan to complete only one semester of biochemistry coursework at Wellesley. Students who plan to continue in Biochemistry II (CHEM 328) should enroll in CHEM 221. Prerequisite: 205, 211 and 212; or 120, 211 and 212 Distribution: Natural and Physical Science Semester: Fall, Spring Unit: 1.25 CHEM 232 Physical Chemistry for the Life Sciences with Laboratory Radhakrishnan An examination of several topics in physical chemistry, with an emphasis on their applications to the life sciences. Topics include quantum chemistry and spectroscopy, molecular mechanics, chemical thermodynamics, and kinetics. Does not count toward the chemistry major, but counts toward the biological chemistry major and chemistry minor. Prerequisite: 205 or 120, or permission of the department; and MATH 116, 116Z, or 120 and PHYS 104 or 107. Not open to students who have taken [231], 233, [332], [333], 334 or 335. Distribution: Natural and Physical Science or Mathematical Modeling. Fulfills the Quantitative Reasoning overlay course requirement. Semester: Spring Unit: 1.25 CHEM 233 Physical Chemistry I with Laboratory Arumainayagam Molecular basis of chemistry; intensive overview of theories, models, and techniques of physical chemistry; extensive coverage of quan-tum mechanics; applications of quantum mechanics to atomic and molecular structure, and spectroscopy; classical thermodynamics of gases and solutions; intermediate topics in chemical kinetics and introduction to reaction dynamics; basic statistical mechanics to calculate thermodynamic variables and equilibrium constants. Prerequisite: 205 or 120, or by permission of the department; and MATH 116, 116Z, or 120 and PHYS 104 or 107. Not open to students who have taken [231], 232, [332], [333], 334, or 335. Distribution: Natural and Physical Science or Mathematical Modeling. Fulfills the Quantitative Reasoning overlay course requirement. Semester: Fall Unit: 1.25 CHEM 250 Research or Individual Study Research is supervised by a member of the Wellesley College chemistry department. Off-campus research requires active participation of a Wellesley faculty member throughout the research period. Course fulfills the research requirement for the major only upon completion of a paper of 8-10 pages on the research and a presentation to the chemistry department during one of the two research seminar presenta-tion periods. A copy of the paper must be submitted to the chair of the chemistry department. (Note: paid internships are not eligible for CHEM 250.) Prerequisite: Open by permission to students who have taken 205 or 120. Distribution: None Semester: Fall, Spring Unit: 1.0
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3.00 Credits
Arumainayagam Topic for 2009-10: Radiation Chemistry. Radiation chemistry is the science of the chemical effects brought about by the absorption of ionizing radiation by matter. This course will examine radiation chemistry in the context of fundamental physiochemical processes, applica-tions, and biological implications. The widespread belief that aging and genetic evolution are both influenced by ambient radiation will be analyzed. Applications of radiation chemistry such as chemical synthesis (e.g., radiation-induced polymerization), food irradiation, steriliza-tion of medical equipment and disposables, waste treatment by irradiation, and semiconductor device manufacture will be discussed. The chemistry of ions, excited states, and radicals will be treated to afford a deeper understanding of matter and its interactions. The central role of low-energy electrons in radiation chemistry will be emphasized. Prerequisites: 211 Distribution: Natural and Physical Science Semester: Spring Unit: 1.0 CHEM 317 Advanced Organic Chemistry Carrico-Moniz Strategies, including retrosynthetic analysis, for the synthesis of complex molecules. Considerable emphasis will be placed on construction of ring systems, acyclic stereocontrol, and asymmetric catalysis. Lecture topics will be accompanied by case studies drawn from the cur-rent chemical literature. Reaction mechanisms will be emphasized throughout the course. Prerequisite: 212 Distribution: Natural and Physical Science Semester: Fall Unit: 1.0
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