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Course Criteria
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3.00 Credits
Beltz, Paul This course will discuss aspects of nervous system development and how these relate to the development of the organism as a whole. Topics such as neural induction, neurogenesis, programmed cell death, axon guidance, synaptogenesis and the development of behavior will be discussed, with an emphasis on the primary literature and critical reading skills. Laboratory sessions focus on a variety of methods used to define developing neural systems. Students may register for either NEUR 306 or BISC 306 and credit will be granted accordingly. Prerequisite: 200 or [ NEUR 213/BISC 213] or BISC 216 or permission of instructor. Distribution: Epistemology and Cognition or Natural and Physical Science Semester: Spring Unit: 1.25
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3.00 Credits
Rodenhouse (Biological Sciences) Topic for 2009-10: Global Change Biology. Environmental conditions for nearly all life forms on Earth are changing at unprecedented rates largely due to human activities: agriculture, deforestation, urbanization, pollution, climate change, transplantation of species, hunting and harvesting. These causes of change and their consequences are not confined by national boundaries or even historical ecological boundaries. This course will examine critically the causes of change, how complex biological systems are studied, and the observed and projected biological consequences of environmental change. Labs will explore how relevant data are gathered and structured for analysis and modeling. Each student will complete an independent project of her choosing on a relevant topic. Students may register for either ES 307 or BISC 307 and credit will be granted accordingly. Prerequisite: Two units in Biological Sciences at the 200-level or above, or permission of the instructor Distribution: Natural and Physical Science Semester: Spring Unit: 1.25
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3.00 Credits
K niger, Helluy NOT OFFERED IN 2009-10. The ecology of coral reefs and rain forests is the focus of the course. Lectures and discussions during the fall prepare students for the field portion in Belize and Costa Rica. The first half of the laboratory takes place on an island bordering the world's second longest barrier reef; the second half is taught in an intact lowland rain forest. Laboratory work is carried out primarily in the field and includes introductions to the flora and fauna, as well as testing of student-generated hypotheses. Normally offered in alternate years. Sub-ject to Dean's Office approval . Prerequisite: 201, 207, or 210, and permission of the instructor. Application required. Distribution: Natural and Physical Science Semester: N/O Unit: 1.25
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3.00 Credits
Hood-DeGrenier Eukaryotic cells possess a diverse array of molecular circuits that regulate their normal activities and respond to external signals. Common modes of regulation include modulation of protein expression or localization, covalent protein modifications, and protein-protein interac-tions. This course will examine the molecular mechanisms that regulate processes such as cell division, cell differentiation, stress res-ponses, and others, in a format that combines lectures and student presentations of current literature articles. A semester-long investiga-tive laboratory project will focus on a particular regulatory pathway using the budding yeast Saccharomyces cerevisiae as a model organ-ism. Prerequisite: 219 or 220 (both recommended) Distribution: Natural and Physical Science Semester: Fall Unit: 1.25
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3.00 Credits
Suzuki The diversity of organismal forms has fascinated human beings for centuries. How did butterflies get eyespots What is the evolutionary origin of bird feathers How did snakes get to be so long The field of evolutionary developmental biology or evo-devo integrates the long separate fields of evolutionary biology and developmental biology to answer these questions. In this course, we will explore topics such as the evolution of novelties, body plan evolution, developmental constraints, convergent evolution and the role of environmental changes in evolution. Through reading of original papers, we will examine recent advances made in evo-devo and critically analyze the role of evo-devo in biology and the implications beyond biology. Students will have the opportunity to design and conduct an independent research project using arthropods. Prerequisite: 202 or 216 or by permission of instructor. Not open to students who have taken [309]. Distribution: Natural and Physical Science Semester: Fall Unit: 1.25
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3.00 Credits
NOT OFFERED IN 2009-10. Topic: Microbial Communication and Development. Many bacteria are social creatures, interacting and communicating with each other. Quorum sensing, where population density alters gene expression, controls a diverse range of behaviors such as virulence factor production, genetic competence, sporulation, biofilm production, and programmed cell death. Signaling pathways and the molecules that regulate them will be studied, as well as the molecular mechanisms that regulate and produce developmental change in prokaryotes. Student participation and discussion of original literature will be emphasized. Prerequisite: 209, 219 or 220, and CHEM 211, or permission of the instructor Distribution: Natural and Physical Science Semester: N/O Unit: 1.0
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3.00 Credits
Tetel Hormones act throughout the body to coordinate basic biological functions such as development, differentiation and reproduction. This course will investigate how hormones act in the brain to regulate physiology and behavior. We will study how the major neuroendocrine axes regulate a variety of functions, including brain development, reproductive physiology and behavior, homeostasis and stress. The reg-ulation of these functions by hormones will be investigated at the molecular, cellular and systems levels. Laboratory experiments will ex-plore various approaches to neuroendocrine research, including the detection of hormone receptors in the brain and analysis of behavior. Students may register for either NEUR 315 or BISC 315 and credit will be granted accordingly. Prerequisite: 200 or [ NEUR 213/BISC 213], or both BISC 110 and BISC 203, or permission of instructor. Distribution: Epistemology and Cognition or Natural and Physical Science Semester: Fall Unit: 1.25
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3.00 Credits
Peterman NOT OFFERED IN 2009-10. Molecular techniques, which allow us to isolate, analyze and manipulate genes, have revolutionized our understanding of living things as well as our ability to alter them genetically. This course focuses on the use of molecular methods to dissect and manipulate complex biological systems. A case-study approach will be used to analyze the application of molecular biology to genetic diseases (e.g., cystic fibrosis and muscular dystrophy), genetically modified organisms, cancer, stem cells, human cloning, aging and envi-ronmental protection. Student participation and critical analysis of the primary literature will be emphasized. In the laboratory students will pursue an original research project using current molecular techniques (e.g., molecular cloning, PCR, DNA sequencing, mutagenesis, protein expression, bioinformatics). Emphasis will be on experimental design and data analysis and interpretation. Prerequisite: 219 or permission of the instructor Distribution: Natural and Physical Science Semester: N/O Unit: 1.25
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3.00 Credits
Sequeira In this course, we will focus on patterns of population differentiation and speciation in oceanic islands. Little is known about the ecological and historical forces responsible for speciation although these are key for the generation of biological diversity. By looking at relationships between organisms, populations and species, we can interpret how historical processes can leave evolutionary footprints on the geograph-ic distribution of traits. After a series of introductory lectures, the course will involve student presentations and discussion of primary litera-ture examining cases in archipelagos (Hawaii, Canaries and Galapagos). In the laboratory, we will explore computational biology tools for analysis of DNA sequences, and apply methods of phylogeny, phylogeography reconstruction and population demographics. We will also explore the growing field of molecular dating of evolutionary events. Prerequisite: 201 or 202 or 210 or 219 or by permission of the instructor. Not open to students who have taken [318]. Distribution: Natural and Physical Science Semester: Spring Unit: 1.25
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3.00 Credits
Ellerby This course will focus on how organisms cope with a complex physical world. Their sophisticated designs withstand large environmental forces, caused by gravity, wind, and water flow. Animals, as well as confronting the problems of not falling over or apart, must overcome additional challenges associated with locomotion. Biomaterials, including spider silk that is stronger than steel and springy tendons that power prodigious jumps, help make this possible. Topics for discussion will include how biomaterials give organisms structure and strength, how muscle acts as a biological motor during locomotion, how animals swim and fly, and how they run, walk and jump effectively on land. Class discussion and student presentation of recent primary literature will be an integral part of the course. Labs will include the analysis of video images to calculate accelerations and power during movement, and the use of force plates to quantify contact forces during running and jumping. Prerequisite: Two units in Biological Sciences at the 200 level or permission of the instructor. Not open to students who have taken 321. Distribution: Natural and Physical Science Semester: Spring Unit: 1.25
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