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Course Criteria
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3.00 Credits
O'Donnell, Suzuki, Skow In this course, we will explore animal development beginning with the process of fertilization. We will consider how a single cell gives rise to the many specialized cell types of the adult and how the development of tissues and the whole body is coordinated. The mechanisms that determine cell fate during embryonic and postembryonic maturation of animals will be discussed. Topics will include: embryonic induc-tion, pattern formation, organ development, regeneration, stem cells, growth, developmental plasticity and aging. Laboratory sessions will focus on experimental approaches to development. Prerequisite: 110 and 111, or permission of the instructor. Distribution: Natural and Physical Science Semester: Spring Unit: 1.25
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3.00 Credits
Griffith (Botany Fellow) Field Botany is a combination of ?What's that wildflower ? and ?Why does it grow over there and not here ? The course merges aspects of plant systematics and identification (with an emphasis on learning the local flora and important plant families) and plant ecology (with an emphasis on ecological interactions and phenomena unique to plants). Laboratories will primarily be taught in the field and greenhouses and will include using dichotomous and Web-based keys to identify plants, observational and experimental studies, and long-term study of forest patches on the Wellesley campus. Laboratories will also include experimental design and data analysis. The goal of Field Botany is not only to train students of botany and plant ecology, but to engage them in botany every time they step outs ide. Students may register for either ES 217 or BISC 217 and credit will be granted accordin gly. Prerequisite: ES 101 or BISC 108 or BISC 111 Distribution: Natural and Physical Science Semester: Fall Unit: 1.
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3.00 Credits
Webb, Sequeira, Beers, Crum The goal of the course is to develop an understanding of the fundamental principles of genetics at the molecular, cellular, and organismal levels. The mechanisms that regulate the control of gene expression leading to alteration in phenotype during cellular differential will be studied. A link will be established between the generation of genetic variants through mutation and recombination, their patterns of inherit-ance, interactions between genes to produce complex phenotypes and the maintenance of such genetic variation in natural populations. Topics will include: organization of the eukaryotic genome, gene structure and function, multi-level gene control, genetics of pattern forma-tion, inheritance of gene differences, gene and allele interactions and aspects of population and evolutionary genetics. Laboratory experi-ments will expose students to the fundamentals of genetics including modern molecular techniques for genetic analysis. Prerequisite: 110 and one unit of college chemistry. Not open to first-year students. Distribution: Natural and Physical Science Semester: Fall Unit: 1.25
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3.00 Credits
Hood-DeGrenier, Beers This course will focus on structure/function relationships in eukaryotic cells. Topics include: protein structure and introductory enzyme ki-netics, membrane and membrane-bound organelle structure and function, cytoskeleton, transport mechanisms, cell communication, cell cycle, apoptosis, and cancer cell biology with an emphasis on experimental methods for investigating these topics. The laboratory consists of three projects: enzyme purification and characterization, investigation of cellular transport pathways in yeast, and an analysis of the cytoskeleton in cultured mammalian cells using fluorescence microscopy. Prerequisite: 110 and two units of college chemistry. One semester of organic chemistry is recommended. Not open to first-year students. Distribution: Natural and Physical Science Semester: Spring Unit: 1.25
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3.00 Credits
Prerequisite: By permission of the instructor. Distribution: None Semester: Fall, Spring Unit: 1.0
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3.00 Credits
Prerequisite: By permission of the instructor. Distribution: None Semester: Fall, Spring Unit: 0.5
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3.00 Credits
Cameron, Paul (Neuroscience) This course takes an integrated approach to the study of organ system function in animals, with an emphasis on human physiology. We will examine control mechanisms that allow the human body to maintain a constant balance in the face of environmental challenges, such as exercise, temperature change, and high altitude. Our particular focus will be recent findings in the areas of neural, cardiovascular, respi-ratory, renal, and muscle physiology. In the laboratory, students gain experience with tools of modern physiological research at both the cellular and organismal levels. Prerequisite: 111 or NEUR 100, and one of the following: 203, 206, [213], NEUR 200 Distribution: Natural and Physical Science Semester: Spring Unit: 1.25
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3.00 Credits
Tjaden NOT OFFERED IN 2009-10. A multidisciplinary course exploring the origins, present and future applications, and challenges of the inter-section of biological and computer sciences. The field of bioinformatics, generated in response to the era of genomics, encompasses all aspects of biological data acquisition, storage, processing, analysis and interpretation with a view to generating in silico models of cellular function. Students may register for either CS 303 or BISC 303 and credit will be granted accordingly. Prerequisites: 231, BISC 219 or BISC 220. Not open to students who have taken CS 313. Distribution: Natural and Physical Science Semester: N/O Unit: 1.0
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3.00 Credits
Staff, Hacopian NOT OFFERED IN 2009-10. Analysis of structure-function relationships of human systems, based principally on microscopic techniques. Examination of selected pathologic states in each system, as well as discussion of recent literature. Laboratory study includes tissue prep-aration for microscopy, as well as hands-on experience at the transmission electron microscope and participation in a group research project. Prerequisite: 206 Distribution: Natural and Physical Science Semester: N/O Unit: 1.25
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3.00 Credits
Buchholtz NOT OFFERED IN 2009-10. A brief history of life. Origin of life from nonlife, evolution of replicatory molecules, origin of eukaryotic cellular structure, diversification of organic domains, kingdoms and animal phyla, development of strategies for life in terrestrial environments, pat-terns of extinction. The course will emphasize student participation and make extensive use of the primary literature. Prerequisite: Two units in Biological Sciences at the 200 level or permission of the instructor. Distribution: Natural and Physical Science Semester: N/O Unit: 1.0
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