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Course Criteria
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4.00 Credits
Develops an understanding of pharmaceutical dosage forms, with emphasis on solids, liquids, semisolids, parenterals, inhalation, and novel drug delivery systems. Combines the discussion of pharmaceutical products developed in industry and those compounded in local pharmacies. Focuses on application of mathematical principles and problem-solving skills in pharmaceutical compounding.
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4.00 Credits
Continues PSC U411. Examines the physical and chemical properties of the drug as it relates to pharmaceutical product development. Covers concepts of thermodynamics, colligative properties, ionic equilibriums and buffers, solubility, complexation and protein binding, reaction kinetics, mass transport, interfacial phenomena and dispersion, and rheology.
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1.00 Credits
Formulates pharmaceutical dosage forms such as powders, capsules, solutions, suspensions, emulsions, ointments, gels, creams, lotions, and suppositories, and tests the quality of the products in the lab using approved methods of analysis. Also provides an understanding of the physical and chemical properties of drugs as they relate to formulation development through experimental observation of dissolution, stability, and effects of pH and co-solvent on solubility of drugs.
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3.00 Credits
Focuses on the basic principles and methods of biopharmaceutics and pharmacokinetics. Covers the kinetics of drug absorption, distribution, metabolism, and excretion; linear and nonlinear pharmacokinetics; general concept of one- and two-compartment models with instantaneous (i.v. bolus), zero order (i.v. infusion), or first order (oral administration or i.m. injection) input; evaluation of bioavailability and investigation of the factors affecting drug availability; influence of the route of administration, dosage form, and regimen on bioavailability of drugs; bioequivalence study; multiple dosing kinetics; general approaches to dosage adjustment in renal disease; noncompartmental analysis; and pharmacokinetic-pharmacodynamic modeling.
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1.00 Credits
Retired August 31, 2006. Offers additional intermediate academic experience by exploring course-related topics in greater depth with the professor. Available only to courses approved by the University Honors Program.
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1.00 Credits
Retired August 31, 2006. Offers additional intermediate academic experience by exploring course-related topics in greater depth with the professor. Available only to courses approved by the University Honors Program.
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1.00 Credits
Retired August 31, 2006. Offers additional intermediate academic experience by exploring course-related topics in greater depth with the professor. Available only to courses approved by the University Honors Program.
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4.00 Credits
Offers elective credit for courses taken at consortium institutions.
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4.00 Credits
Offers elective credit for courses taken at consortium institutions.
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4.00 Credits
Offers elective credit for courses taken at consortium institutions.
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