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Course Criteria
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3.00 Credits
Description of transition metal-containing systems found in biology. Structural and electronic properties and reactivity of metalloproteins, metalloenzymes, and metallocofactors. Methods used to probe and model metal sites by spectroscopic and synthetic techniques. Offered: Sp, even years.
Prerequisite:
either CHEM 224, CHEM 239, or CHEM 337; CHEM 416
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3.00 Credits
Introduction to modern instrumental methods of chemical analysis, including chromatography, optical and mass spectroscopy, electrochemistry and flow injection analysis. Basic concepts of transducers, spectrometers, mass analysis, separation sciences, and computerized data acquisition and reduction. Includes laboratory. Offered: W.
Prerequisite:
CHEM 321
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3.00 Credits
Sampling and sample dissolution, multiple chemical equilibria, pH and electrochemical measurement, reagent-based kinetic enzyme assays and immunoassays. Principles of process, environmental, clinical, and biotechnological assays. Separations and flow injection.
Prerequisite:
either CHEM 223, CHEM 237, or CHEM 335; CHEM 321
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3.00 Credits
Modern instrumental methods of bioanalysis of DNA and proteins, including agarose gel electrophoresis, PCR, Sanger sequencing for nucleic acid analysis and ELISA, SDS-PAGE, and LC/MS-MS analysis of proteins. Mass analysis, separation sciences, and bioinformatics tools. Includes laboratory. No credit allowed if BIOC 426 taken. Offered: Sp.
Prerequisite:
CHEM 239; either CHEM 317, CHEM 321, CHEM 461 or BIOC 440
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3.00 Credits
Introduction to modern separation techniques such as gas chromatography, highperformance liquid chromatography, electrophoresis, and field flow fractionation. Offered: W.
Prerequisite:
either CHEM 224, CHEM 239, or CHEM 337; either CHEM 241, CHEM 321, or CHEM 346
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3.00 Credits
Molecular orbital theory in organic chemistry. Woodward-Hoffmann rules, aromaticity, concerted reactions, photochemical transformations, and reactions of electron-deficient species. Offered: alternate years.
Prerequisite:
either CHEM 239 or CHEM 337
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3.00 Credits
Survey of the statics and dynamics of biophysical and biochemical processes. Offered: alternate years; W.
Prerequisite:
either CHEM 224, CHEM 239, or CHEM 337; either CHEM 453, CHEM 455, or CHEM 475, any of which may be taken concurrently; recommended: either BIOC 405 or BIOC 440
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3.00 Credits
Enzyme structure, function, chemistry and inhibition, including modes of biological catalysis, stereochemistry, enzyme characterization and kinetics, and design and principles of enzyme inhibitors. Also major classes of natural products, their chemistry, biological activity, biosynthesis, physiological role, and ecological significance. Offered: alternate years; Sp.
Prerequisite:
either CHEM 224, CHEM 239, or CHEM 337; recommended: either BIOC 405 or BIOC 440
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3.00 Credits
Chemistry of DNA, RNA, peptides, and proteins. Solid phase chemical synthesis. Manual and automated sequencing. Conformational analysis. Peptide mimetics and protein design. Interaction of DNA with drugs and toxins. Triple helices and antisense oligonucleotides.
Prerequisite:
either CHEM 239 or CHEM 337
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3.00 Credits
No course description available.
Prerequisite:
Separate File
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