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  • BIOS 20234: Molecular Biology of the Cell

    3.00 Credits
    University of Chicago

    PQ: Score of 5 on the AP biology test. This course covers the fundamentals of molecular and cellular biology. Topics include protein structure and function; DNA replication, repair, and recombination; transcription, translation, and control of gene expression; cellular structure; cell division; protein modification and stability; cellular signaling; and cell growth, cell death, and cancer biology. V. Prince, M. Glotzer, R. Zaragoza. Autumn. L.
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  • BIOS 20235: Biological Systems

    3.00 Credits
    University of Chicago

    PQ: BIOS 20234. Students preparing for the health professions must take BIOS 20235 and 20242 in sequence. This course builds upon molecular cell biology foundations to explore how biological systems function. Topics include classical and molecular genetics, developmental signaling networks, genomics, proteomics, transcriptomics, and biological networks. I. Rebay, V. Prince, R. Zaragoza. Winter. L.
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  • BIOS 20242: Principles of Physiology

    3.00 Credits
    University of Chicago

    PQ: BIOS 20235 or consent of instructor. Students preparing for the health professions must take BIOS 20235 and 20242 in sequence. This course focuses on the physiological problems that animals (including humans) face in natural environments; solutions to these problems that the genome encodes; and the emergent physiological properties of the molecular, cellular, tissue, organ, and organismal levels of organization. We emphasize physiological reasoning, problem solving, and current research. M. Feder. Spring. L.
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  • BIOS 20243: From Neurons to Behavior:The Morphological and Physiological Basis of Movement

    3.00 Credits
    University of Chicago

    PQ: BIOS 20235 and first-year standing, or consent of instructor. This course meets requirements for the biological sciences major. This course examines movement systems at multiple levels of design and function-integrating neurobiology, muscle morphology and physiology, skeletal mechanics, and the interaction of organisms with the physical environment. These topics are examined through lectures, readings from the primary literature, and labs. Lectures provide basic information on each subject and examples of recently published work. Readings complement the lectures and cover current issues in the relevant fields. Labs involve exposure to methodological approaches and work on a class research project that combines data collected with several of these techniques. M. Hale. Spring. Not offered 200 9 -10. L.
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  • BIOS 20244: The BIO 2010 University of Chicago Initiative:Biophysics and Chemical Biology

    3.00 Credits
    University of Chicago

    PQ: BIOS 20234 and first-year standing. This interdisciplinary seminar course is designed to prepare students for research at the interface of physical and biological sciences. Papers are selected from those recently published by colleagues at the University of Chicago, allowing students to meet and interact with authors and to explore examples of approaches drawn from the physical sciences and applied as powerful tools to understand biological systems. Working in groups, the students master the contents of each paper. They then conduct critical reviews, both in class and by writing essays. Through lab demonstrations and visits, students are introduced to key research methods and the shared research labs that provide access to key technologies to scientists at the University of Chicago. S. Kron. Spring.
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  • BIOS 20245: Immersive Virtual Anatomy

    3.00 Credits
    University of Chicago

    PQ: BIOS 20235, 20183, or 20193, or consent of instructor. This course is an intensive introduction to human anatomy in a unique lab without cadaveric materials. Students and instructors collaborate in systematically revealing and learning fine anatomic details of the human body systems and regions from high-resolution clinical volumetric data (e.g., computed tomography and magnetic resonance) via high-performance interactive full-color stereo visualization systems based upon parallel computer gaming boards. This captivating, larger-than-life "dissection" experience is complemented by our study of textbooks and other virtual anatomic materials . J. C. Silverstein. Spring.
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  • BIOS 20246: Photons to Consciousness

    3.00 Credits
    University of Chicago

    PQ: BIOS 20235 or consent of instructor. This course uses the visual system as a model to explore how the brain works. We begin by considering the physical properties of light. We then proceed to consider the mechanism of sensory transduction, cellular mechanisms of neuron to neuron communication, the operation of small neural networks, strategies of signal detection in neuron networks, and the hierarchical organization of cortical function. We conclude with visually guided behavior and consciousness. E. Schwartz. Spring.
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  • BIOS 20249: Genome Informatics:Genome Organization,Expression,and Transmission

    3.00 Credits
    University of Chicago

    PQ: BIOS 20235. This seminar course examines how genomes are organized for coding sequence expression and transmission to progeny cells. The class discusses a series of key papers in the following areas: bacterial responses to external stimuli and genome damage, control of eukaryotic cell differentiation, complex loci regulating developmental expression in animals, centromere structure and function, position effect variegation, chromatin domains, chromatin remodeling, RNAi, and chromatin formatting. J. Shapiro. Spring.
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  • BIOS 20250: Programming for Modern Biological Science Research

    3.00 Credits
    University of Chicago

    PQ: BIOS 20235, 20182, or 20192. In the era of "omics" (e.g., genomics, proteomics), many modern biological studies require the automation of lab procedures and the processing of massive data. This course helps students acquire basic programming skills to face the challenge. We introduce basic concepts about computing and programming, as well as describe daily computing environment. We discuss the use of basic Perl, C, Java, MySQL database, and other programming for biological research needs (i.e., repetitive or massive calculations, formating of text data, sequence manipulation). C. Liu. Spring. L.
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  • BIOS 20256: Developmental Genetics and Evolution

    3.00 Credits
    University of Chicago

    PQ: BIOS 20235. The purpose of this course is to provide a developmental genetic perspective on evolutionary questions that have emerged in various disciplines (e.g., developmental biology, paleontology, phylogenetic systematics). Topics range from the evolution of gene regulation to the origin of novelties (e.g., eyes, wings). Although these subjects are introduced in lectures, the focus of this course is on reading, presenting, and discussing original research papers. U. Schmidt-Ott. Spring.
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