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Course Criteria
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3.00 Credits
PQ: BIOS 10110 or 10130. This course provides a general evolutionary framework for the 360 living and 470 fossil primate species. Applications of chromosomal studies (karyology) and biomolecular comparisons (molecular phylogenetics) are also covered. Other topics include principles of classification, principles of phylogenetic reconstruction, scaling effects of body size, primates in the context of mammal evolution, diets and dentitions, locomotor morphology and behavior, morphology and function of sense organs, evolutionary aspects of the brain, reproductive biology, and social organization. Each lecture concludes with implications for human evolution. R. Martin. Spring.
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3.00 Credits
PQ: BIOS 10110 or 10130. This course is designed to give students an overview of the many functions of the brain, including perception, movement, language, emotion, memory, and sleep. We use a model of disease or dysfunction in an area of the brain to understand its normal functioning. This approach is complemented by presenting modern methods such as functional MRI and by reviewing historical milestones in neuroscience. Attendance required at each class meeting, including lectures, labs, review sessions, and screenings of videotapes and imaging sessions. A. Noronha. Spring.
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3.00 Credits
PQ: BIOS 10110 or 10130. This course examines how the brain generates behavior. Topics include the organization of the nervous system; the mechanisms by which the brain translates external stimuli into electrical and chemical signals to initiate or modify behavior; and the neurological bases of learning, memory, sleep, cognition, drug addiction, and neurological disorders. M. McNulty. Spring, Summer.
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3.00 Credits
PQ: BIOS 10110 or 10130. This course explores selected examples of ancient, re-emerging, and emerging pathogens in the context of biology, as well as epidemiology and the selective pressures that influence the spread and control of epidemics. Emphasis is placed on the biological basis of how microbes gain access to and cause damage in their hosts and the struggle between the pathogen and the host's immune system. Students also gain an understanding of the basis for diagnostic procedures, treatments, and immunization. Discussion sessions required in addition to lectures. S. Boyle-Vavra. Winter.
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3.00 Credits
PQ: BIOS 10110 or 10130 (no equivalency). In this lecture/discussion course, the molecular biology and clinical aspects of cancer are considered in tandem. In particular, the most prevalent malignant tumors (e.g., those arising in the breast, prostate, colon, and lung) are used as examples. T. W. Wong. Autumn.
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3.00 Credits
PQ: BIOS 10110 or 10130. This course explores biological poisons and toxins found throughout our environment. Toxins can originate from bacteria (anthrax, tetanus, botulinum, cholera); plants (ricin, curare, opiates); marine organisms (tetrodotoxin, saxitoxin); mushrooms (amanitin); frogs (batrachotoxin); and other organisms. Emphasis is placed on toxins that provide insight into the workings of the nervous, cardiovascular, and gastrointestinal systems. We also address current topics (e.g., weaponization of toxins in biowarfare and bioterrorism) and explore examples of therapeutic (i.e., Botox) and commercial uses of toxins. J. Kyle. Spring.
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3.00 Credits
PQ: BIOS 10110 or 10130. Infectious diseases are a major cause of human deaths globally, yet many are preventable and curable. Why are people still dying What would it take to prevent, cure, and ultimately eliminate infectious disease By focusing on the major killers of our time (i.e., lower respiratory infections, AIDS, diarrheal diseases, tuberculosis, and malaria), we learn from past successes and failures, while exploring novel approaches and technologies. This course takes a multi-faceted approach, considering both biological (i.e., genetics, evolution, ecology) and nonbiological (i.e., sociological, economic) factors. I. Pavlova. Autumn.
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3.00 Credits
PQ: BIOS 10110 or 10130. This lecture/discussion course examines the multi-step process by which normal cells become malignant cancer cells. Topics include how defects in the regulation of proliferation, differentiation, and apoptosis can occur in cancer cells, as well as how cancer cells can acquire the ability to attract blood vessels (angiogenesis) and to invade other organ systems (metastasis). We emphasize the study of signal transduction pathways and how they are altered in cancer cells. The concept of genes that cause cancer (oncogenes) and genes that deter cancer (tumor suppressor genes) is discussed. New disease treatments that target specific molecular defects within cancer cells are reviewed. M. Villereal. Winter.
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3.00 Credits
PQ: Open to students with first-year standing who plan to major in biological sciences or to prepare for a career in the health professions and whose exposure to biology in high school may have been limited. Must be taken in sequence with BIOS 20141. This course does not meet requirements in the Biological Sciences major. This is an introductory biology course intended to give a basic knowledge of the chemical and biochemical basis of biology. We cover basic chemical concepts pertinent to understanding cell biology, including the chemistry of biological chemical bonds, pH, thermodynamics, chemical equilibrium, chemical kinetics, enzyme kinetics, organic molecules, and relevant organic reactions. We also introduce proteins, lipids, and carbohydrates. P. Strieleman. Winter.
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3.00 Credits
PQ: BIOS 20140. Open to students with first-year standing who plan to major in biological sciences or to prepare for a career in the health professions and whose exposure to biology in high school may have been limited. This course does not meet requirements in the Biological Sciences major. This introductory course reviews principal concepts in Cell Biology to prepare students for the Fundamental Cell and Molecular Biology sequences. Topics include cell structures and their functions; the role of biological macromolecules; cell respiration; DNA replication, transcription, and translation; and the cell cycle. In the lab, students learn the basics of fluorescent microscopy to study the cell and some of its organelles. Students also learn study skills so they can master biological concepts and write formal lab reports. R. Zaragoza. Spring. L.
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