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Course Criteria
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3.00 Credits
PQ: BIOS 10110 or 10130. Selected topics of current medical and/or environmental interest are used to illustrate basic principles of cell and molecular biology. T. Martin. Spring.
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3.00 Credits
PQ: BIOS 10110 or 10130. This course attempts to show how the interdependence of observations and ideas leads to the development of scientific disciplines. Because the instructor is a biochemist, some examples are selected from developments in this field, which has vagaries that provide opportune material for instructive generalizations radiating into other biological and chemical areas. An attempt is made to determine reasons for the development, and the lack of development, of scientific disciplines at different times and in different places. H. Friedmann. Autumn.
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3.00 Credits
PQ: BIOS 10110 or 10130. This course explores the biological evidence and theories that seek to explain gender in humans. This course relies on current research in neuroscience, physiology, and cell biology to address topics such as the genetics of gender; sexual differentiation of the fetus; sexually dimorphic brain regions; the biology of gender identity and gender preference; and hormonal/environmental contributions to gender. M. Osadjan. Autumn.
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3.00 Credits
PQ: BIOS 10110 or 10130. Simplistic explanations of the biological basis of human sexuality rely on the qualitative/quantitatively different chromosomal constitution of males and females. Current biological research indicates that the situation is much more complex. This course considers the molecular structure of X and Y chromosomes and the control mechanisms that govern their function. Social consequences considered range from the use of the Y chromosome for the study of human history to the supposed roles of genes in homosexuality and in behavioral characteristics. B. Strauss. Spring.
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3.00 Credits
PQ: BIOS 10110 or 10130. Our understanding of animal evolution has changed quite dramatically over the past twenty years, as new data from the application of DNA technologies has challenged the "textbook" view of animal evolution. The first part of this course introduces animal phyla, and we discuss the ideas of how major organizational changes in animal body plans occurred very early in animal evolution. The remaining part of this course introduces the new molecular data now being used in comparative animal biology and how this has revolutionized our understanding animal evolution. These data include developmental genetics, genomics, and molecular phylogenetics . C. Lowe. Winter.
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3.00 Credits
PQ: BIOS 10110 or 10130. The implications of the double helical structure of DNA triggered a revolution in cell biology. More recently, the technology to sequence vast stretches of DNA has offered new vistas in fields ranging from human origins to the study of biodiversity. This course considers a set of these issues, including the impact of a DNA perspective on the legal system, on medicine, and on conservation biology. A. Turkewitz, M. Nobrega. Winter.
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3.00 Credits
PQ: BIOS 10110 or 10130. This discussion-based course examines virulence strategies of different infectious agents that have persisted throughout history up to the present day. Special emphasis is given to host defense and innate immunity. Topics include vaccine development, HIV/AIDs, immune-evasion, and emerging infectious diseases (e.g., SARS, hemorrhagic fevers). W. DePaolo. Spring.
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3.00 Credits
PQ: BIOS 10110 or 10130. This course studies the application of cell biology principles to physiological stress. We use paradigms (e.g., fasting) to talk about organ interactions (e.g., the Cori cycle). This includes discussions of receptors, kinases, and other cellular biology. M. Musch. Autumn.
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3.00 Credits
PQ: BIOS 10110 or 10130. This course examines the underlying biological mechanisms of nutrient utilization in humans and the scientific basis for setting human nutritional requirements. The relationships between food choices and human health are also explored. Students consider how to assess the validity of scientific research that provides the basis for advice about how to eat healthfully. Class assignments are designed to help students apply their knowledge by critiquing their nutritional lifestyle, nutritional health claims, and/or current nutrition policy issues. P. Strieleman. Summer.
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3.00 Credits
PQ: BIOS 10110 or 10130. This course discusses basic concepts involved in the functioning of the cardiopulmonary system, followed by various types of patho-physiological stresses experienced by the lungs and heart. We discuss how these systems adapt to stress conditions by turning on "emergency response" mechanisms at the molecular, cell, tissue, and organ levels. We also discuss current strategies and drugs designed to treat maladaptive changes taking place in the heart and lungs under stress . M. Gupta, K. Birukov. Spring.
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