20 490J - Foundations of Computational and Systems Biology

Institution:
Massachusetts Institute of Technology
Subject:
Description:
Provides an introduction to computational and systems biology. Includes units on the analysis of protein and nucleic acid sequences, protein structures, and biological networks. Presents principles and methods used for sequence alignment, motif finding, expression array analysis, structural modeling, structure design and prediction, and network analysis and modeling. Techniques include dynamic programming, Markov and hidden Markov models, Bayesian networks, clustering methods, and energy minimization approaches. Exposes students to emerging research areas. Designed for students with strong backgrounds in either molecular biology or computer science. Some foundational material covering basic programming skills, probability and statistics is provided for students with less quantitative backgrounds. Students taking graduate version complete additional assignments.
Credits:
3.00
Credit Hours:
Prerequisites:
Prereq: Biology (GIR); 7.05 or 5.07; 1.00, 1.001, or 6.00; or permission of instructor
Corequisites:
Exclusions:
Level:
Instructional Type:
Lecture
Notes:
Additional Information:
Historical Version(s):
Institution Website:
Phone Number:
(617) 253-1000
Regional Accreditation:
New England Association of Schools and Colleges
Calendar System:
Four-one-four plan

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