20 213 - DNA Damage and Genomic Instability

Institution:

Massachusetts Institute of Technology

Subject:

Description:

Focuses on the biochemistry and molecular mechanisms of DNA replication and DNA repair. Analyzes the chemistry of DNA damaging events, and continues with analysis of the mutagenic and toxic consequences of modifications to DNA structure. Also presents the contrasting perspective that normal DNA processing leads to mutations. Moves from analysis and discussion of key DNA repair pathways to connections between DNA repair and human diseases. Discussion of current literature and in-depth discussions of the chemistry and biochemistry of DNA metabolism form the foundation of the subject.

Credits:

2.00

Credit Hours:

Prerequisites:

Prereq: 5.07, 7.05, permission of instructor

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

web.mit.edu/student/

Phone Number:

(617) 253-1000

Regional Accreditation:

New England Association of Schools and Colleges

Calendar System:

Four-one-four plan

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