20 111J - Physical Chemistry of Biomolecular Systems

Institution:

Massachusetts Institute of Technology

Subject:

Description:

Provides a quantitative approach to understanding the physical and chemical laws that govern the behavior of biological macromolecules. Basic thermodynamics, state of a system, state variables. Work, heat, first, second, and third laws of thermodynamics. Entropy and its statistical basis, free energy representations, Legendre transforms, Maxwell relations, Gibbs function, Boltzmann distribution and partition functions. Equilibrium properties of macroscopic and microscopic systems; macromolecular structure and interactions in solution. Driving forces for molecular self-assembly. Binding, cooperativity, solvation, and titration of macromolecules. Applications of introductory quantum mechanics to spectroscopy.

Credits:

5.00

Credit Hours:

Prerequisites:

Prereq: Calculus II (GIR), Chemistry (GIR), Physics I (GIR); Coreq: Physics II (GIR)

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

web.mit.edu/student/

Phone Number:

(617) 253-1000

Regional Accreditation:

New England Association of Schools and Colleges

Calendar System:

Four-one-four plan

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