BIOS 1218 - Developmental Biology

Institution:

Yeshiva University

Subject:

Biomedical Sciences (Graduate)

Description:

1218 DEVELOPMENTAL BIOLOGY COURSE LEADER: Dr. Nick Baker CREDITS/CLASS MEETINGS: 3 semester hours, approximately 25 class meetings, 1-1/2 hours each. This year's course will be organized around discussion of current and emerging topics in developmental biology. In addition to formal presentations, faculty will also facilitate presentations by small groups of students for some of the sessions. Evaluation will be based on presentations and class participation. There will be no examinations. PREREQUISITE BACKGROUND: Most students will have taken Molecular Genetics and Gene Expression or equivalent courses. However, students (including first years) without this background can be considered on an individual basis, and should see the course leader for advice. SUGGESTED BACKGROUND READING: Select from Alberts et al., Molecular Biology of the Cell, 4th edition 2002, Chapter 21; Hartwell et al., Genetics - from Genes to Genomes, 3rd edition 2008, Chapters 18 & 20; relevant chapters of "Developmental Biology", by Scott F. Gilbert, (Sinauer Associates, 5th edition 1997); relevant chapters of Squire et al "Fundamental Neuroscience", 2nd edition Academic Press 2002; The Art of Genes - how Organisms Make Themselves, by Enrico Coen, OUP 2000. SUITABILITY FOR 1ST YEAR STUDENTS: Yes, with suitable undergraduate preparation, or if they have taken the courses equivalent to those described above. COURSE DESCRIPTION: Developmental biology impacts nearly all areas of biology and medicine, representing the integration of classical embryology, modern molecular genetics, and systems biology. Discoveries in developmental biology contribute to mechanisms as diverse as signal transduction, cell proliferation, differentiation, and morphogenesis, and affect our perspective of fields ranging from evolution to cancer. In the future, developmental biology will continue to play an important role in understanding birth defects and pathogenic processes throughout life, and in understanding stem cells and regenerative medicine. Topics in the Developmental Biology course are chosen by the participating faculty and are relevant to developmental problems that are being investigated at AECOM. They will include birth defects, cardiac defects and development, eye induction and development; stem cells, asymmetric cell divisions, and cellular polarity; neuronal development, axon pathfinding, and the maintenance of neuronal connections throughout life; morphogen signaling, developing signaling pathways and signal transduction, and developmental systems biology. The course material does not concentrate on any particular organism. Aspects of mouse and human development, Xenopus and zebrafish, C. elegans and Drosophila will be included, and conserved molecular and evolutionary aspects of development are expected to be common themes.

Credits:

3.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.yu.edu

Phone Number:

(212) 960-5400

Regional Accreditation:

Middle States Association of Colleges and Schools

Calendar System:

Semester

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