BIOS 1107 - Mechanisms of Disease

Institution:

Yeshiva University

Subject:

Biomedical Sciences (Graduate)

Description:

1107 MECHANISMS OF DISEASE COURSE LEADER: Dr. Bridget Shafit-Zagardo CREDITS/CLASS MEETINGS: 3 semester hours; Approximately 22 lectures will be given by prominent guest lecturers and AECOM faculty. PREREQUISITE BACKGROUND: Knowledge of Immunology and Biochemistry is helpful. SUITABILITY FOR 1ST YEAR STUDENTS: Yes. COURSE DESCRIPTION: This multidisciplinary course will investigate the pathobiology of human diseases and relevant animal models. Topics will include cellular pathology and the mechanisms of cell injury and repair. The course will emphasize the immunologic, molecular, genetic, and biochemical mechanisms that result in the gross and microscopic changes taking place within affected tissues. Types of injury to be explored in depth will include: biochemical/genetic (Vera-delete diabetes and sickle cell anemia from within the paranthesis) (expansion of trinucleotide repeats, chromosomal abnormalities, cancer), inflammatory (Multiple Sclerosis, atherosclerosis), infectious (Acquired Immunodeficiency Syndrome and Tuberculosis), environmental (DNA damage). The pathobiology of aging, senescence and cell death will be examined in detail. Lectures will include Einstein faculty and prominent guest lecturers within the field. The course requirements will be assigned readings, an oral presentation and a final exam. NOTE: Class size limited to 29

Credits:

3.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.yu.edu

Phone Number:

(212) 960-5400

Regional Accreditation:

Middle States Association of Colleges and Schools

Calendar System:

Semester

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