EECS 359 - Bioinformatics in Practice

Institution:

Case Western Reserve University

Subject:

Description:

This course covers basic computational methods of organizing and analyzing biological data, targeting senior and junior level students from both mathematical/computational sciences and life sciences. The aim of the course is to provide the students with basic skills to be able to understand molecular biology data and associated abstractions (sequences, structure, gene expression, molecular network data), access to available resources (public databases, computational tools on the web). Implement basic computational methods for biological data analysis, and use understanding of these methods to solve other problems that arise in biological data analysis. Topics covered include DNA and protein sequence databases, pairwise sequence alignment and sequence search (dynamic programming, BLAST), multiple sequence alignment (HMMs, CLUSTAL-W), sequence clustering, motif finding, pattern matching, phylogenetic analysis (tree reconstruction, neighbor joining, maximum parsimony, maximum likelihood), gene finding, functional annotation, biological ontologies, analysis of gene expression data, and network biology (protein protein interactions, topology, modularity).

Credits:

3.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.case.edu

Phone Number:

(216) 368-2000

Regional Accreditation:

North Central Association of Colleges and Schools

Calendar System:

Semester

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