EBME 408 - Engineering Tissues/Materials - Learning from Nature's Paradigms

Institution:

Case Western Reserve University

Subject:

Description:

This course aims to provide students with a foundation based on "nature's" design and optimization" criteria for engineering tissues and biomaterials. This will be achieved through focused review of the principles of development, wound healing, regeneration, and repair through remodeling, using nature as a paradigm. Principles of transport will be explored quantitatively and in relation to multi-organismal evolution. Cellular engineering principles will be explored, including current state of the art in stem cell physiology and therapeutic applications. Endogenous engineering approaches to surgical tissue reconstruction will be analyzed. An overview of contemporary approaches to tissue and cell engineering will be given, including tissue scaffold design, use of bioreactors in tissue engineering, and molecular surface modifications for integration of engineered tissues in situ. Fundamental engineering principles will be augmented through case studies involving specific applications. Ethical considerations related to clinical non-clinical application of tissue and cell engineering technology will be integrated into each lecture. Prereq: Graduate standing or Undergraduate with Junior or Senior standing and a cumulative GPA of 3.2 or above.

Credits:

3.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.case.edu

Phone Number:

(216) 368-2000

Regional Accreditation:

North Central Association of Colleges and Schools

Calendar System:

Semester

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