MB&B 535 - Protein Folding: From Misfolding to Disease

Institution:

Wesleyan University

Subject:

Molecular Biology and Biochemistry

Description:

Amyloidogenesis, the process by which proteins and peptides misfold to form amyloid fibers, is at the root of several different diseases, including Parkinson's disease, Alzheimer's disease, mad cow disease and type II diabetes to name a few. This course will focus on current research in the field that seeks to understand why a functional well-folded protein adopts the misfolded amyloid form. In the course of discussing the misfolded nature of these proteins, we will review central elements of protein structure and stability to better understand the protein-folding landscape and the process of misfolding. We will also discuss how the process of misfolding leads to the different diseases and disease pathologies.

Credits:

0.50

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.wesleyan.edu

Phone Number:

(860) 685-2000

Regional Accreditation:

New England Association of Schools and Colleges

Calendar System:

Semester

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