CHM 543 - Advanced Topics in Structural Biology - Neuro-developmental Disorders from a Molecular Point of View

Institution:

Princeton University

Subject:

Description:

A critical discussion of biological structures pertinent to understanding neurodevelopmental diseases. Crystal structures of ion channels, synaptic scaffolds, receptors, chromatin remodeling complexes, and kinases will be analyzed in the context of recent genetic findings on the causes of autism, fragile-X syndrome, and Rett's syndrome. A systems biology approach will be taken to bridge the gap between behavioral phenotypes, as studied with mouse models, and gene expression profiles. The principles of x-ray crystallography will be taught as needed to follow journal articles under discussion.

Credits:

0.00 - 4.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.princeton.edu

Phone Number:

(609) 258-3000

Regional Accreditation:

Middle States Association of Colleges and Schools

Calendar System:

Semester

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