INTERDIS 100B - Molecules And Cells

Institution:

Duke University

Subject:

Interdisciplinary

Description:

A course designed for first year medical students that focuses on the molecular and cellular principles of human disease. The course has four components, which are tightly integrated: biochemistry, cell biology, genetics, and a series of clinical correlations. The biochemistry component re-emphasizes the relationship between structure and function of the major classes of macromolecules in living systems including proteins, carbohydrates, lipids, and nucleic acids. The metabolic interrelationships and control mechanisms are discussed as well as the biochemical basis of human diseases. The cell biology component emphasizes the structure and function of the cells and tissues of the body. The laboratory provides practical experience with light microscopy studying and analyzing the extensive slide collection of mammalian tissues. The genetics component emphasizes molecular aspects of the human genome, the structure of complex genes, regulation of gene expression, experimental systems for genetic analysis, human genetics -- including population genetics and genetic epidemiology, the use of genetic analysis for the identification of disease causing genes, cytogenetics, cancer genetics, and genetic diagnosis and counseling. The series of clinical correlations links the material covered in the basic science lectures to clinical problems. Many of the correlations include an interview with a patient. Secondary contact: Margaret Briggs, m.briggs@cellbio.duke.edu. To view more about the course schedule, please refer to BlueDocs. Credit: 8. Enrollment: max 105. Mariano Garcia-Blanco, MD/PhD; Kenneth Kreuzer, PhD; Michael Hershfield, MD; Tom McIntosh, PhD; Fred Schachat, PhD, Margaret Briggs, PhD; and staff

Credits:

6.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

WWW.DUKE.EDU

Phone Number:

(919) 684-8111

Regional Accreditation:

Southern Association of Colleges and Schools

Calendar System:

Semester

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