Genetics 147 - Animal Development and Human Disease

Institution:

Dartmouth College

Subject:

Description:

10S: Arrange Offered in alternate years. Understanding of the molecular basis of human disease results from the exceptional power of genetic research technologies in the model organisms (worms, flies, fish and mice) and the universal nature of major genetic pathways in the animal kingdom. This course will offer integrated examination of the genetic, cellular, and molecular bases of the biology and pathology of development. The topics will be focused on the most interesting and informative human hereditary diseases for which the responsible genes have been identified. The developmental principles and pathways (e.g., Wnt signaling and colorectal cancer, sex determination and sex reversal, left-right asymmetry and human laterality disorders, DNA repair and Li-Fraumeni syndrome) and the model organisms we will use to illustrate them may vary somewhat from year to year. 1 hour of lecture and 3 hours of discussion per week. Prerequisite: permission of an instructor. Tevosian, Ahmed, Conradt, Ernst, Saito.

Credits:

1.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.dartmouth.edu

Phone Number:

(603) 646-1110

Regional Accreditation:

New England Association of Schools and Colleges

Calendar System:

Quarter

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