Biological Sciences 39 - Computational Molecular Biology

Institution:

Dartmouth College

Subject:

Description:

09W, 10W: 10A Computers and computer programs have become essential tools in modern molecular biology. As the amount of DNA and protein sequence data continues to grow, the use and understanding of these computational tools is becoming increasingly important. Deriving biological understanding from sequence data requires sophisticated computer analyses while demanding from molecular biologists the ability to interpret intelligently the results from these analyses. Not only can these programs provide the biologist with information about his or her sequence of interest, but a solid understanding of these tools can also be used to make predictions of biological phenomena that can be tested in the lab. This course will explore computational molecular biology through both lectures and hands-on computer experimentation through homework assignments. This course will discuss approaches to analyzing protein and DNA sequences and will foster an understanding of how to extract biologically relevant information from the numerous databases containing all this information. Topics will include basic computer architecture and operating systems, database design and searching, sequence comparisons, pattern discovery, genome comparisons, gene discovery, determining evolutionary relationships, RNA and protein structure predictions, data mining, and DNA array analysis. No computer programming experience is needed, but familiarity with using the Internet is recommended. Prerequisites: Biology 13. Dist: SCI. Gross.

Credits:

3.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.dartmouth.edu

Phone Number:

(603) 646-1110

Regional Accreditation:

New England Association of Schools and Colleges

Calendar System:

Quarter

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