AIRF 3501 - Diagnostic Techniques for the Biomedical Sciences

Institution:

University of Connecticut-Tri-Campus

Subject:

Description:

(260) (Also offered as PVS 3501.) Second semester. Two credits. One 1-hour lecture and one 3-hour laboratory. Prerequisite: Open to juniors or higher; instructor consent required;. open only to students who have declared the Agricultural Biotechnology minor and passed MCB 3414. Recommended preparation: MCB 2000. Anamani, Frasca, Lipcius, Risatti Theoretical basis and practical exposure to modern laboratory methods used in the biomedical sciences for disease diagnosis. biochemical basis of cell transformation, proliferation, and metastasis will be covered, followed by discussions of molecular mechanisms by which environmental chemicals interact with DNA and other cellular components. Metabolic activation of genotoxic carcinogens will be covered in detail, and the importance of polymorphisms in activating enzymes among human sub-populations will be discussed in terms of individual risks of cancer. Activation of protooncogenes, inactivation of tumor suppressor genes, and the role of these proteins in regulating the cell cycle will be covered in detail. Approaches for estimating human risk of cancer based on exposure estimates and biological markers will also be presented.

Credits:

2.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.uconn.edu

Phone Number:

(860) 486-2000

Regional Accreditation:

New England Association of Schools and Colleges

Calendar System:

Semester

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