STAT 473 - Bioinformatics

Institution:

University of Pennsylvania

Subject:

Description:

Ewens. Prerequisite(s): Good background in probability and statistics at the approximate level of STAT 430 and STAT 431. The material will follow the class textbook, Ewens and Grant "Statistical Models in Bioinformatics", Springer, second edtion, 2005. An introduction to the use of statistical methods in the increasingly important scientific areas of genomics and bioinformatics. The topics to be covered will be decided in detail after the initial class meeting, but will be taken from the following: - background probability theory of one and many random variables and of events; background statistical inference theory, classical and Bayesian; Poisson processes and Markov chain; the analysis of one and many DNA sequences, in particular shotgun sequencing, pattern analysis and motifs; substitution matrices, general random walk theory, advanced statistical inference, the theory of BLAST, hidden Markov models, microarray analysis, evolutionary models.

Credits:

3.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.upenn.edu

Phone Number:

(215) 898-5000

Regional Accreditation:

Middle States Association of Colleges and Schools

Calendar System:

Semester

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