CAMB 510 - Immunology for CAMB Students

Institution:

University of Pennsylvania

Subject:

Description:

Y. Chen, G. Silvestri, J. Wherry. Prerequisite(s): BIOM 600 or instructor permit. Priority given to students in the MVP & GTV programs of CAMB. CAMB students only. The purpose of this course is to give a thorough grounding in Immunology to Cell and Molecular Biology graduate students with an emphasis on the role of the immune system in combating infectious and neoplastic disease and its role in immunopathological states such as transplantation rejection, autoimmunity and allergy. This will be a required course for CAMB students in the Microbiology, Virology and Parasitology program and the Vaccine and Gene Therapy program, replacing Immune Mechanisms 506. It may also be used as an elective by other CAMB students such as Cancer Biology and Cell Biology and Physiology. The course is divided, by topic, into three parts. The first deals with innate and adaptive immune mechanisms, the structure, function, and molecular biology of antigen receptors and major histocompatibility complex molecules; the development and differentiation of lymphocytes and other hematopoietic cells involved in immunity and mechanisms of lymphocyte circulation and memory. The second part will cover the immune response in infection by bacteria, viruses and parasites and how this impacts on vaccine design and active immunization strategies. The course concludes by focusing on the immune system's role in pathological states such as cancer, allergy, graft rejection and autoimmunity. The formal part of the course is comprised of two 1.5 hour lectures per week. In addition each week there will be an informal 1.5-hour meeting, on Fridays, which will be used to introduce the students to specialized techniques used to measure immune responses or to discuss topical issues relating to the application of immunological knowledge in fighting disease with emphasis on the primary literature in the field. There will be two exams. The first will be taken after part I and the second after part II and III of the course.

Credits:

3.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.upenn.edu

Phone Number:

(215) 898-5000

Regional Accreditation:

Middle States Association of Colleges and Schools

Calendar System:

Semester

The Course Profile information is provided and updated by third parties including the respective institutions. While the institutions are able to update their information at any time, the information is not independently validated, and no party associated with this website can accept responsibility for its accuracy.