CAMB 483 - Epigenetics

Institution:

University of Pennsylvania

Subject:

Description:

Wagner. Prerequisite(s): BIOL 221. This course will investigate epigenetic phenomena: heritable alternative states of gene activity that do not result from altered nucleotide sequence. Recent findings suggest an important role of these phenomena in normal development, as well as in oncogenesis. Many, but not all, epigenetic phenomena are based on the fact that in the organism DNA is organized into a higher order structure, the chromatin. We will therefore first discuss the implications of chromatin for gene activity. We will then investigate epigenetic phenomena such as DNA methylation, genomic imprinting, RNA interference, silencing, and co-suppression. This course is a combination of lecture and discussion using current scientific literature.

Credits:

3.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.upenn.edu

Phone Number:

(215) 898-5000

Regional Accreditation:

Middle States Association of Colleges and Schools

Calendar System:

Semester

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