ENG BE 561 - DNA and Protein Sequence AnalysisPrereq

Institution:

Boston University

Subject:

Description:

ENG BE 209 and ENG BE 200, or equivalent. Fundamental concepts from molecular biology and molecular genetics are presented. Biological inferences are made from DNA and protein sequence data using mathematical and computer science techniques. Pairwise sequence comparative analyses and homolog identification are studied in detail. The dynamic programming algorithm is extended to deal with more general cases and is applied to RNA structure prediction. Additional topics include: multiple sequence alignment and conserved sequence pattern recognition methods, phylogenetic tree reconstruction to study molecular evolution, methods of identifying coding regions in genomic data, algorithms to solve the fragment assembly problem of DNA sequencing, techniques for physical mapping, mathematical models and computations alogrithms for genetic regulation. An introduction to protein 3-dimensional structure predictions is also given. 4 cr.

Credits:

4.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.bu.edu

Phone Number:

(617) 353-2000

Regional Accreditation:

New England Association of Schools and Colleges

Calendar System:

Semester

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